NR2F1 and MAP6

Number of citations of the paper that reports this interaction (PubMedID 15604093)
0

Data Source:
HPRD (two hybrid)

		NR2F1	MAP6
Description		nuclear receptor subfamily 2 group F member 1	microtubule associated protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cis-Golgi Network Cytoskeleton Microtubule Membrane Axon Dendrite Transport Vesicle Membrane Cytoplasmic Vesicle Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Calmodulin Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Signal Transduction Nervous System Development Negative Regulation Of Neuron Projection Development Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Cytoskeleton-dependent Intracellular Transport Lysosome Localization Dendrite Morphogenesis Positive Regulation Of Axonogenesis Regulation Of Microtubule Cytoskeleton Organization
Pathways		Nuclear Receptor transcription pathway
Drugs		beta-Naphthoflavone
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical volume ( 32963231) Left–right brain asymmetry ( 33723403) PR interval ( 32439900) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: AHR BCL11A BCL11B CBX5 COPS2 EEF1D ESR1 FOXP1 FOXP2 FOXP4 GTF2B HNF4A ISL1 MAP6 MCPH1 NCOA1 NCOA2 NCOA3 NCOR2 NSD1 PFDN1 PHB2 POU2F2 RXRA SP1 THRA UBC	7 interacting genes: GRSF1 NR2F1 RARB RARG RORB TRAF1 TUBB
Entrez ID		7025	4135
HPRD ID		00584	15989
Ensembl ID		ENSG00000175745	ENSG00000171533
Uniprot IDs		A0A8V8TQQ6 P10589	Q96JE9
PDB IDs		2EBL
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Chromatin Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Intracellular Receptor Signaling Pathway Sequence-specific DNA Binding Nuclear Receptor Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleoplasm DNA-templated Transcription Sequence-specific Double-stranded DNA Binding Negative Regulation Of Metabolic Process DNA Binding Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Estrogen Receptor Binding Transcription Cis-regulatory Region Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Nucleus Nuclear Receptor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Thyroid Hormone Receptor Signaling Pathway TBP-class Protein Binding Positive Regulation Of Macromolecule Metabolic Process Hormone-mediated Signaling Pathway Rhythmic Process Response To Lipid	Nuclear Receptor Activity Glandular Epithelial Cell Development Intracellular Receptor Signaling Pathway Growth Plate Cartilage Development Nuclear Retinoid X Receptor Binding Sequence-specific DNA Binding Columnar/cuboidal Epithelial Cell Development Cartilage Development Involved In Endochondral Bone Morphogenesis Negative Regulation Of Chondrocyte Differentiation Sequence-specific Double-stranded DNA Binding Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Stem Cell Proliferation Embryonic Hindlimb Morphogenesis Embryonic Eye Morphogenesis Negative Regulation Of Cartilage Development DNA-binding Transcription Factor Activity Hindlimb Morphogenesis Regulation Of Myelination Regulation Of Chondrocyte Differentiation Positive Regulation Of RNA Metabolic Process Eye Morphogenesis Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Sensory Organ Morphogenesis Regulation Of Cartilage Development RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Connective Tissue Development Bone Development Cellular Response To Retinoic Acid Stem Cell Proliferation Embryonic Morphogenesis Embryonic Limb Morphogenesis Regulation Of Stem Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Limb Morphogenesis Cartilage Development Multicellular Organism Growth Nuclear Receptor-mediated Signaling Pathway Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Retinoic Acid Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Organ Morphogenesis Positive Regulation Of Mitochondrial RNA Catabolic Process Epithelial Cell Development RNA Polymerase II Transcription Regulator Complex Growth Plate Cartilage Chondrocyte Growth Negative Regulation Of RNA Metabolic Process
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