AGO3 and ATP6V0D2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AGO3	ATP6V0D2
Gene Name		argonaute RISC catalytic component 3	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytosol Membrane RISC Complex Micro-ribonucleoprotein Complex	Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Extracellular Vesicular Exosome
	Molecular Function	Protein Binding MiRNA Binding Poly(A) RNA Binding	Protein Binding Hydrogen Ion Transmembrane Transporter Activity
	Biological Process	MRNA Catabolic Process Epidermal Growth Factor Receptor Signaling Pathway Notch Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Gene Expression Posttranscriptional Gene Silencing Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Stem Cell Proliferation	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Regulatory RNA pathways Cellular Senescence Signaling by Wnt Signaling by EGFRvIII in Cancer Oncogene Induced Senescence Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation PI-3K cascade Pre-NOTCH Transcription and Translation PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Pre-NOTCH Expression and Processing Post-transcriptional silencing by small RNAs Innate Immune System Signaling by PDGF Signalling by NGF DAP12 interactions GAB1 signalosome Signaling by NOTCH Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by ERBB4 MicroRNA (miRNA) biogenesis Signaling by Overexpressed Wild-Type EGFR in Cancer Role of LAT2/NTAL/LAB on calcium mobilization PI3K events in ERBB4 signaling Signaling by FGFR beta-catenin independent WNT signaling Signaling by ERBB2 Signaling by EGFR Ca2+ pathway Oxidative Stress Induced Senescence Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Small interfering RNA (siRNA) biogenesis Adaptive Immune System	Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS			Adverse response to lamotrigine and phenytoin ( 22379998)
Protein-Protein Interactions		4 interactors: ATP4B ATP6V0D2 BDNF SLC22A2	5 interactors: ADRM1 AGO3 NDUFB8 RBM15B RPS3
Entrez ID		192669	245972
HPRD ID		09558	16522
Ensembl ID		ENSG00000126070	ENSG00000147614
Uniprot IDs		B4E1P5 Q9H9G7	Q8N8Y2
PDB IDs
Enriched GO Terms of Interacting Partners?		Ion Transport Monovalent Inorganic Cation Transport Response To Anesthetic Response To Fluoxetine Response To L-glutamate Response To Organonitrogen Compound Cation Transmembrane Transport Hydrogen Ion Transmembrane Transport Taste Bud Development Regulation Of Retinal Cell Programmed Cell Death Dendrite Extension Cellular Response To Norepinephrine Stimulus Cation Transport Proton Transport Ion Transmembrane Transport Axon Target Recognition Response To Norepinephrine Response To Ether Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Synaptic Transmission, GABAergic Choline Transport Response To Potassium Ion Transmembrane Transport Transport Regulation Of Short-term Neuronal Synaptic Plasticity Response To Light Intensity Chronic Inflammatory Response Cellular Response To Organonitrogen Compound Neurotransmitter Biosynthetic Process Secretion By Cell Response To Drug Histamine Transport Quaternary Ammonium Group Transport Response To Auditory Stimulus Synaptic Transmission Response To Food Glutamate Secretion Secretion Cellular Response To Catecholamine Stimulus Response To Organic Substance Anion Transport Cellular Response To Nerve Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Vitamin A Negative Regulation Of Neuroblast Proliferation Neurotransmitter Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Transferrin Transport Drug Transmembrane Transport	MRNA Metabolic Process Positive Regulation Of DNA N-glycosylase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process Nitrogen Compound Metabolic Process Translational Initiation Regulation Of Translation RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Gene Expression Proteasome Assembly Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cytoplasmic Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Viral Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Protein Metabolic Process Biosynthetic Process Translation Gene Silencing By MiRNA Transcription, DNA-templated Posttranscriptional Gene Silencing RNA Biosynthetic Process Mitochondrial Electron Transport, NADH To Ubiquinone
Tagcloud ?		aberrant ago4 biogenesis cancerous carcinogenesis cigarette combinations components deregulation dgcr8 dicer encodes etiological hbv hcc hepatocarcinogenesis hepatocellular implicated integrated mirna multicentric occurrence p68 p72 paired piwil4 prognosis promoters trimethylation	chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation
Tagcloud (Difference) ?		aberrant ago4 biogenesis cancerous carcinogenesis cigarette combinations components deregulation dgcr8 dicer encodes etiological hbv hcc hepatocarcinogenesis hepatocellular implicated integrated mirna multicentric occurrence p68 p72 paired piwil4 prognosis promoters	chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally
Tagcloud (Intersection) ?		trimethylation