ATP6V0D2 and ADRM1

Number of citations of the paper that reports this interaction (PMID 19818731)
3

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ATP6V0D2	ADRM1
Gene Name		ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	adhesion regulating molecule 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Extracellular Vesicular Exosome	Proteasome Complex Nucleoplasm Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Hydrogen Ion Transmembrane Transporter Activity	Protease Binding Protein Binding Endopeptidase Activator Activity Proteasome Binding
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation	Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Endopeptidase Activity Proteasome Assembly
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998)	Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: ADRM1 AGO3 NDUFB8 RBM15B RPS3	16 interactors: APP ATP6V0D2 DDI1 EGFR PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 UBE3A UBQLN1 UBQLN2 UCHL5
Entrez ID		245972	11047
HPRD ID		16522	06440
Ensembl ID		ENSG00000147614	ENSG00000130706
Uniprot IDs		Q8N8Y2	Q16186
PDB IDs			2KQZ 2KR0 2L5V
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process Positive Regulation Of DNA N-glycosylase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process Nitrogen Compound Metabolic Process Translational Initiation Regulation Of Translation RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Gene Expression Proteasome Assembly Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cytoplasmic Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Viral Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Protein Metabolic Process Biosynthetic Process Translation Gene Silencing By MiRNA Transcription, DNA-templated Posttranscriptional Gene Silencing RNA Biosynthetic Process Mitochondrial Electron Transport, NADH To Ubiquinone	Regulation Of Protein Catabolic Process Regulation Of Proteolysis Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Cellular Macromolecule Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Protein Polyubiquitination Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Proteolysis Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cellular Amino Acid Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Mitotic Cell Cycle Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Cellular Response To DNA Damage Stimulus Regulation Of Cellular Ketone Metabolic Process Cellular Protein Metabolic Process Regulation Of Cell Cycle Arrest Protein Metabolic Process Mitotic Cell Cycle Phase Transition
Tagcloud ?		chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation	bassoon carbohydrate deficits enables glcnac glcnacation implication interplay isotopic itraq lectin ltq mapped mek2 overlap p25 piccolo plasticity polymerization pqd proteasomal proteomics pulsed quantitation rpn13 synapses synapsin synaptic tubulin
Tagcloud (Difference) ?		chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation	bassoon carbohydrate deficits enables glcnac glcnacation implication interplay isotopic itraq lectin ltq mapped mek2 overlap p25 piccolo plasticity polymerization pqd proteasomal proteomics pulsed quantitation rpn13 synapses synapsin synaptic tubulin
Tagcloud (Intersection) ?