ATP6V0D2 and PHF12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	PHF12
Description		ATPase H+ transporting V0 subunit d2	PHD finger protein 12
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Nucleus Nucleoplasm Transcription Repressor Complex Sin3-type Complex
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	Transcription Corepressor Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	7 interacting genes: ATP6V0D2 BRCA1 H3-4 HDAC1 MORF4L1 SHANK3 SIN3A
Entrez ID		245972	57649
HPRD ID		16522	15123
Ensembl ID		ENSG00000147614	ENSG00000109118
Uniprot IDs		Q8N8Y2	Q96QT6
PDB IDs			2L9S 2LKM 8BPA 8BPB 8BPC 8C60
Enriched GO Terms of Interacting Partners?		NF-kappaB Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Nucleoplasm Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II	Sin3-type Complex Chromatin Organization Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone Deacetylase Complex Forebrain Neuron Differentiation Condensed Nuclear Chromosome Epigenetic Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Heterochromatin P53 Binding Neuron Differentiation Transcription Repressor Complex Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Regulation Of Stem Cell Population Maintenance Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Krueppel-associated Box Domain Binding Guanylate Kinase-associated Protein Clustering Plasma Membrane Proton-transporting V-type ATPase Complex Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Binding Regulation Of Cell Cycle G2/M Phase Transition Protein Lysine Delactylase Activity Fungiform Papilla Formation Nucleosome Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation BRCA1-B Complex Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Via Homologous Recombination Protein Decrotonylase Activity Histone Decrotonylase Activity Spermatogonial Cell Division Central Nervous System Neuron Differentiation Synaptic Receptor Adaptor Activity Negative Regulation Of Cytoskeleton Organization Cellular Response To Indole-3-methanol Positive Regulation Of Developmental Process Regulation Of Developmental Process Hair Follicle Placode Formation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?