ATP6V0D2 and RPS3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	RPS3
Gene Name		ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	ribosomal protein S3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm Mitochondrial Inner Membrane Spindle Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Ruffle Membrane Extracellular Vesicular Exosome NF-kappaB Complex
	Molecular Function	Protein Binding Hydrogen Ion Transmembrane Transporter Activity	Damaged DNA Binding MRNA Binding Structural Constituent Of Ribosome DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Protein Binding Oxidized Purine Nucleobase Lesion DNA N-glycosylase Activity Enzyme Binding Protein Kinase Binding Poly(A) RNA Binding Protein Kinase A Binding NF-kappaB Binding Iron-sulfur Cluster Binding
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Catabolic Process, Endonucleolytic Cytoplasmic Translation DNA Repair Transcription, DNA-templated Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Negative Regulation Of DNA Repair Positive Regulation Of NF-kappaB Transcription Factor Activity Cell Division Positive Regulation Of DNA N-glycosylase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998)
Protein-Protein Interactions		5 interactors: ADRM1 AGO3 NDUFB8 RBM15B RPS3	14 interactors: ATP6V0D2 CCT2 CSNK2A1 FOLH1 HSP90AA1 IL7R MDM2 NDRG1 NFKB1 RELA RPL9 SUMO1 TP53 YWHAQ
Entrez ID		245972	6188
HPRD ID		16522	10941
Ensembl ID		ENSG00000147614	ENSG00000149273
Uniprot IDs		Q8N8Y2	P23396
PDB IDs			1WH9 3J3A
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process Positive Regulation Of DNA N-glycosylase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process Nitrogen Compound Metabolic Process Translational Initiation Regulation Of Translation RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Gene Expression Proteasome Assembly Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cytoplasmic Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Viral Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Protein Metabolic Process Biosynthetic Process Translation Gene Silencing By MiRNA Transcription, DNA-templated Posttranscriptional Gene Silencing RNA Biosynthetic Process Mitochondrial Electron Transport, NADH To Ubiquinone	Cellular Response To Alkaloid Immune Response Positive Regulation Of MiRNA Metabolic Process Membrane Organization Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Protein Localization To Organelle Immune System Process Cellular Response To Nicotine Signal Transduction DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Regulation Of MiRNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Signal Transduction In Response To DNA Damage Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signaling Cellular Response To Hypoxia Cellular Response To Peptide Hormone Stimulus Response To Organic Substance Cellular Response To Decreased Oxygen Levels Chaperone-mediated Protein Complex Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Communication Cellular Response To Peptide Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Cellular Response To Organic Substance Protein Localization Membrane Protein Intracellular Domain Proteolysis Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process Negative Regulation Of Gene Expression Response To UV Regulation Of Protein Catabolic Process Negative Regulation Of Biosynthetic Process Cellular Protein Localization Innate Immune Response Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Alkaloid Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Response To Oxidative Stress Protein Targeting Regulation Of Apoptotic Process
Tagcloud ?		chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl2 rpl20 rpl22 rpl23 rpl33 rpoa rps11 rps12 rps18 rps8 secx ugg
Tagcloud (Difference) ?		chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl2 rpl20 rpl22 rpl23 rpl33 rpoa rps11 rps12 rps18 rps8 secx ugg
Tagcloud (Intersection) ?