ATP6V0D2 and NDUFB8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	NDUFB8
Description		ATPase H+ transporting V0 subunit d2	NADH:ubiquinone oxidoreductase subunit B8
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Respiratory Chain Complex I
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Monoatomic Ion Transport Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis
Drugs		Tiludronic acid	NADH
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)	Brain morphology (MOSTest) ( 32665545) Palmitoleic acid (16:1n-7) levels ( 23362303)
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70
Entrez ID		245972	4714
HPRD ID		16522	11886
Ensembl ID		ENSG00000147614	ENSG00000166136
Uniprot IDs		Q8N8Y2	O95169
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		NF-kappaB Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Nucleoplasm Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II
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