DUSP6 and ZNF212

Number of citations of the paper that reports this interaction (PubMedID 18255255)
0

Data Source:
BioGRID (two hybrid)

		DUSP6	ZNF212
Description		dual specificity phosphatase 6	zinc finger protein 212
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Tyrosine/threonine Phosphatase Activity Hydrolase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Tyrosine Phosphatase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	MAPK Cascade Signal Transduction Response To Xenobiotic Stimulus Cell Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Apoptotic Process Negative Regulation Of MAPK Cascade Response To Nitrosative Stress Regulation Of Heart Growth ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Response To Growth Factor	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Dendrite Development Positive Regulation Of Transcription By RNA Polymerase II Neuromuscular Process Controlling Balance Neuron Apoptotic Process General Adaptation Syndrome, Behavioral Process Walking Behavior Response To Alcohol
Pathways		RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway Signaling by MAPK mutants	Generic Transcription Pathway
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Aspartate aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 29325848 30478444) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: AATK ERBB4 LMTK2 LTK MAPK1 MAPK3 MDFI ROR2 SRPK1 TEX11 TXK ZNF212	31 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DRC4 DUSP6 FAM90A1 FHL2 FXR1 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3
Entrez ID		1848	7988
HPRD ID		04124	03859
Ensembl ID		ENSG00000139318	ENSG00000170260
Uniprot IDs		Q16828 Q53GP9	A0A090N8N3 B3KQE6 Q9UDV6
PDB IDs		1HZM 1MKP
Enriched GO Terms of Interacting Partners?		Protein Kinase Activity Kinase Activity Protein Tyrosine Kinase Activity Protein Phosphorylation Phosphorylation Protein Autophosphorylation ATP Binding ERBB2 Signaling Pathway Protein Serine Kinase Activity Interleukin-34-mediated Signaling Pathway Protein Serine/threonine Kinase Activity Nucleotide Binding Transferase Activity Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Golgi Inheritance Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Neuroinflammatory Response Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Peptidyl-tyrosine Autophosphorylation Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Bergmann Glial Cell Differentiation Receptor Complex Enzyme-linked Receptor Protein Signaling Pathway ERBB Signaling Pathway Insulin Receptor Signaling Pathway Cellular Developmental Process MAP Kinase Activity GABA Receptor Binding Regulation Of Golgi Organization Pseudopodium Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Positive Regulation Of Macrophage Chemotaxis Gland Development Glial Cell Differentiation Positive Regulation Of Neuroinflammatory Response Animal Organ Formation Face Development Peptidyl-threonine Phosphorylation Stress-activated MAPK Cascade Cell Development	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Intracellular Signal Transduction Cellular Response To Amino Acid Starvation Regulation Of Metabolic Process Response To Amino Acid Starvation Negative Regulation Of ERK1 And ERK2 Cascade Nucleoplasm DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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