DRP2 and DTNA

Number of citations: 0 (PubMedID 10767429)
Data Source: HPRD (in vitro)

		DRP2	DTNA
Name		dystrophin related protein 2	dystrobrevin alpha
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Perikaryon Synapse Glutamatergic Synapse	Nucleoplasm Cytoplasm Plasma Membrane Membrane Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Cell Projection Intermediate Filament Cytoskeleton Synapse
	Molecular Function	Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding Metal Ion Binding
	Biological Process	Central Nervous System Development Synapse Organization Synaptic Signaling	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Synaptic Signaling
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
GWAS		No GWAS studies recorded	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444 ) PR interval ( 32439900 ) Urate levels in overweight individuals ( 25811787 )
Interacting Genes		4 interacting genes: DAG1 DTNA PRX UTRN	16 interacting genes: ACTA1 APPL1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN
Entrez ID		1821	1837
HPRD ID		02083	03141
Ensembl ID		ENSG00000102385	ENSG00000134769
Uniprot IDs		Q13474	A0A7P0T9L1 A0A7P0TBH9 A0A7P0Z4D7 B7Z3X3 Q9Y4J8
PDB IDs		Not available	2E5R
GO Terms Enriched among Interactors		Sarcolemma Contractile Ring Vinculin Binding Dystrophin-associated Glycoprotein Complex Synaptic Signaling Positive Regulation Of Cell-matrix Adhesion Cell-cell Signaling Filopodium Signaling Axon Ensheathment Muscle Attachment Cell Communication Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Calcium-dependent Cell-matrix Adhesion Synapse Retrograde Trans-synaptic Signaling By Trans-synaptic Protein Complex Nerve Maturation Muscle Contraction Regulation Of Cell-substrate Adhesion Postsynaptic Membrane Dystroglycan Complex Response To Denervation Involved In Regulation Of Muscle Adaptation Trans-synaptic Signaling By Trans-synaptic Complex Laminin-1 Binding Schwann Cell Differentiation Photoreceptor Ribbon Synapse Muscle System Process Response To Muscle Inactivity Peripheral Nervous System Myelin Maintenance Trans-synaptic Signaling Dystroglycan Binding Protein-containing Complex Binding Response To Inactivity Branching Involved In Salivary Gland Morphogenesis Actin Binding Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Costamere Cellular Response To Sterol Positive Regulation Of Cell Adhesion Node Of Ranvier Laminin Binding Schwann Cell Development Nuclear Periphery Skeletal Muscle Tissue Regeneration Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Commissural Neuron Axon Guidance Angiogenesis Involved In Wound Healing Axon Regeneration Morphogenesis Of An Epithelial Sheet	Dystrophin-associated Glycoprotein Complex Sarcolemma Syntrophin Complex Muscle Contraction Muscle System Process Actin Binding Vinculin Binding Structural Molecule Activity Cytoskeleton Regulation Of Sodium Ion Transmembrane Transport System Process Regulation Of Sodium Ion Transport Protein-containing Complex Filopodium Nitric-oxide Synthase Binding Neuromuscular Junction PDZ Domain Binding Plasma Membrane Costamere Structural Constituent Of Cytoskeleton Regulation Of Monoatomic Ion Transmembrane Transport Synapse Filopodium Membrane Myosin Binding Regulation Of Transport Positive Regulation Of Endocytosis Anchoring Junction Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Monoatomic Ion Transport Cardiac Muscle Cell Action Potential Structural Constituent Of Muscle Calmodulin Binding Regulation Of Heart Contraction Fast-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cytoplasm Postsynaptic Membrane Regulation Of Blood Circulation Lateral Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Postsynaptic Density Glutamatergic Synapse Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Neurofilament Cytoskeleton Positive Regulation Of Macropinocytosis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Actin Cytoskeleton Signaling Striated Muscle Contraction Cell Communication