DRP2 and PRX

Number of citations: 0 (PubMedID 11430802)
Data Source: HPRD (two hybrid, in vitro)

		DRP2	PRX
Name		dystrophin related protein 2	periaxin
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Perikaryon Synapse Glutamatergic Synapse	Nucleus Cytoplasm Plasma Membrane Membrane Anchoring Junction
	Molecular Function	Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Central Nervous System Development Synapse Organization Synaptic Signaling	Axon Ensheathment Peripheral Nervous System Myelin Maintenance Regulation Of RNA Splicing
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Diseases		None	Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		No GWAS studies recorded	Otitis media ( 27632927 ) Otitis media (chronic) ( 27632927 ) Otitis media (recurrent) ( 27632927 )
Interacting Genes		4 interacting genes: DAG1 DTNA PRX UTRN	3 interacting genes: CDK6 DRP2 TERF2IP
Entrez ID		1821	57716
HPRD ID		02083	05758
Ensembl ID		ENSG00000102385	ENSG00000105227
Uniprot IDs		Q13474	A0A669KBF1 Q9BXM0
PDB IDs		Not available	4CMZ
GO Terms Enriched among Interactors		Sarcolemma Contractile Ring Vinculin Binding Dystrophin-associated Glycoprotein Complex Synaptic Signaling Positive Regulation Of Cell-matrix Adhesion Cell-cell Signaling Filopodium Signaling Axon Ensheathment Muscle Attachment Cell Communication Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Calcium-dependent Cell-matrix Adhesion Synapse Retrograde Trans-synaptic Signaling By Trans-synaptic Protein Complex Nerve Maturation Muscle Contraction Regulation Of Cell-substrate Adhesion Postsynaptic Membrane Dystroglycan Complex Response To Denervation Involved In Regulation Of Muscle Adaptation Trans-synaptic Signaling By Trans-synaptic Complex Laminin-1 Binding Schwann Cell Differentiation Photoreceptor Ribbon Synapse Muscle System Process Response To Muscle Inactivity Peripheral Nervous System Myelin Maintenance Trans-synaptic Signaling Dystroglycan Binding Protein-containing Complex Binding Response To Inactivity Branching Involved In Salivary Gland Morphogenesis Actin Binding Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Costamere Cellular Response To Sterol Positive Regulation Of Cell Adhesion Node Of Ranvier Laminin Binding Schwann Cell Development Nuclear Periphery Skeletal Muscle Tissue Regeneration Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Commissural Neuron Axon Guidance Angiogenesis Involved In Wound Healing Axon Regeneration Morphogenesis Of An Epithelial Sheet	Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Negative Regulation Of DNA Recombination At Telomere Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Shelterin Complex Protection From Non-homologous End Joining At Telomere Nuclear Telomere Cap Complex Type B Pancreatic Cell Development Protein Localization To Chromosome, Telomeric Region Telomere Capping G-rich Strand Telomeric DNA Binding Lateral Ventricle Development Telomere Maintenance In Response To DNA Damage Regulation Of Hematopoietic Stem Cell Differentiation Astrocyte Development Regulation Of Monocyte Differentiation Generation Of Neurons Hematopoietic Stem Cell Differentiation Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Senescence RNA-templated DNA Biosynthetic Process Dentate Gyrus Development Cyclin-dependent Protein Serine/threonine Kinase Activity Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Nuclear Chromosome Cyclin Binding