FLII and TRAIP

Number of citations of the paper that reports this interaction (PMID 9671805)
11

Data Source:
HPRD (in vitro, two hybrid)

		FLII	TRAIP
Gene Name		flightless I homolog (Drosophila)	TRAF interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Focal Adhesion	Nucleolus Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding	Ubiquitin-protein Transferase Activity Receptor Signaling Protein Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Muscle Contraction Multicellular Organismal Development Actin Cytoskeleton Organization Actin Filament Severing	Apoptotic Process Signal Transduction Cell Proliferation Protein Ubiquitination Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MYD88 OPTN PRMT1 TRAIP	22 interactors: APP CYLD FLII MAPRE2 POLK RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2
Entrez ID		2314	10293
HPRD ID		02647	05811
Ensembl ID		ENSG00000177731	ENSG00000183763
Uniprot IDs		Q13045	Q9BWF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Modification Signal Transduction Chromatin Organization Peptidyl-arginine N-methylation Signaling Cell Communication Histone Arginine Methylation Intracellular Estrogen Receptor Signaling Pathway Peptidyl-arginine Methylation Response To Stimulus Chromosome Organization Chromatin Remodeling Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling ATP-dependent Chromatin Remodeling Histone H3-R17 Methylation Positive Regulation Of Type I Interferon Production Histone Modification Histone H3-R2 Methylation Cell Development Regulation Of Type I Interferon Production Prostate Epithelial Cord Elongation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Methylation Response To Molecule Of Fungal Origin Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Receptor Recycling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Interleukin-23 Production Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of RNA Metabolic Process Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Protein Methylation Regulation Of Growth Regulation Of Cellular Process Defense Response Golgi Ribbon Formation Establishment Of Endothelial Intestinal Barrier Regulation Of Organ Morphogenesis Defense Response To Bacterium See more	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Protein Metabolic Process Innate Immune Response-activating Signal Transduction Catabolic Process Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteolysis MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Programmed Cell Death Cell Death Death Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Proteolysis Cellular Metabolic Process Cellular Response To Stress Immune Response-regulating Signaling Pathway Innate Immune Response Cellular Response To Hypoxia Immune Response Cellular Response To Decreased Oxygen Levels Defense Response Positive Regulation Of Proteolysis Regulation Of Cell Cycle Cellular Response To Oxygen Levels Positive Regulation Of Immune Response Regulation Of Protein Catabolic Process Regulation Of Gene Expression See more
Tagcloud ?		a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming	anteroventral aromatization avpv bcl2 cyclic dense describing dictated estradiol fertility herein historical hypothalamus lh luteinizing males mammals nfkappab perinatal periventricular perspective proposing rodents surge testosterone tnfalpha tonic triggered update
Tagcloud (Difference) ?		a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming	anteroventral aromatization avpv bcl2 cyclic dense describing dictated estradiol fertility herein historical hypothalamus lh luteinizing males mammals nfkappab perinatal periventricular perspective proposing rodents surge testosterone tnfalpha tonic triggered update
Tagcloud (Intersection) ?