SEPT1 and SEPT5

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		SEPT1	SEPT5
Gene Name		septin 1	septin 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Midbody	Cytoskeleton Plasma Membrane Cell Cortex Synaptic Vesicle Terminal Bouton
	Molecular Function	Protein Binding GTP Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding
	Biological Process	Cell Cycle Cell Division	Cytokinesis Metabolic Process Synaptic Vesicle Targeting Regulation Of Exocytosis Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS			DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		8 interactors: AMOT APP AURKB SEPT12 SEPT5 SEPT6 TEX11 TOLLIP	18 interactors: APP KAT7 LSM8 MAGEA2B MAPK6 MYOG PARK2 PFN2 SEPT1 SEPT10 SEPT11 SEPT2 SEPT4 SEPT6 SEPT7 SEPT8 STX1A STX4
Entrez ID		1731	5413
HPRD ID		15324	04100
Ensembl ID		ENSG00000180096	ENSG00000184702
Uniprot IDs		J3KNL2 Q8WYJ6	G3XAH0 Q99719
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytokinesis Cell Division Cell Cycle Cell Cycle Process Cellular Localization Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Synaptic Growth At Neuromuscular Junction Histone H3-S28 Phosphorylation Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Meiotic Gene Conversion Spindle Stabilization Collateral Sprouting Axon Midline Choice Point Recognition Abscission Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Cellular Component Assembly Axon Choice Point Recognition Cleavage Furrow Formation Mitotic Spindle Midzone Assembly Positive Regulation Of Cell Cycle Process Chromosome Segregation Mitotic Spindle Elongation Synaptic Vesicle Targeting Chiasma Assembly Neuron Remodeling Protein Localization To Endosome Negative Regulation Of Cytokinesis Protein Localization To Kinetochore Regulation Of Binding Spindle Midzone Assembly Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Cell Cycle Positive Regulation Of Protein Sumoylation Resolution Of Meiotic Recombination Intermediates Negative Regulation Of Vascular Permeability Response To Light Stimulus Exocytosis Positive Regulation Of Cell Size Cell Migration Involved In Gastrulation	Cell Cycle Cell Division Regulation Of Synaptic Vesicle Transport Regulation Of Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Synaptic Transmission Positive Regulation Of Protein Ubiquitination Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Regulation Of Synaptic Vesicle Exocytosis Regulation Of Insulin Secretion Regulation Of Protein Ubiquitination Regulation Of Peptide Hormone Secretion Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Muscle Atrophy Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Secretion Positive Regulation Of Exocytosis Organelle Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Secretion Organelle Fusion Sperm Mitochondrion Organization Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Embryonic Cell Shape Positive Regulation Of Protein Metabolic Process Vesicle Docking Cellular Component Assembly Exocytosis Regulation Of Cellular Component Organization Membrane Docking Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Regulation Of Protein Localization Regulation Of Protein Secretion Cytokinesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of L-glutamate Transport Neurotransmitter Secretion
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