SEPTIN1 and SEPTIN3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SEPTIN1	SEPTIN3
Description		septin 1	septin 3
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Meiotic Spindle	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Septin Complex Cell Division Site Synapse Presynapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Spindle Assembly Involved In Female Meiosis Intracellular Protein Localization Regulation Of Exocytosis Cell Division Meiotic Metaphase Chromosome Alignment Cytoskeleton-dependent Cytokinesis	Intracellular Protein Localization Cell Division Cytoskeleton-dependent Cytokinesis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: AMOT APP AURKB DDIT4L DNAJB13 GORASP2 GPSM1 HSF2BP LNX1 MID2 MRPL12 NIF3L1 PICK1 PIH1D1 SDCBP SEPTIN11 SEPTIN3 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC UBE2I	23 interacting genes: CDC37 CHRM3 CKS1B CREBBP DDIT4L EIF6 GABARAPL2 LASP1 MAP1LC3B MAPK6 MOB1A NTAQ1 PELI2 PRKG1 RNF4 RNF8 RSPH1 SDCBP SELENOF SEPTIN1 SLC39A14 SNCA WBP2
Entrez ID		1731	55964
HPRD ID		15324	10515
Ensembl ID		ENSG00000180096	ENSG00000100167
Uniprot IDs		J3KNL2 Q8WYJ6	A0A2R8Y4H2 Q9UH03
PDB IDs		6WBE	3SOP 4Z51 4Z54 6UQQ
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Molecular Adaptor Activity Microtubule Cytoskeleton Cell Division Cytoplasm GTPase Activity Intracellular Protein Localization Cytoskeleton GTP Binding Regulation Of Receptor Internalization Stress Fiber Synaptonemal Complex Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Synaptic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Frizzled Binding Interleukin-5 Receptor Complex SUMO Conjugating Enzyme Activity Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Phosphoprotein Binding Septin Collar Meiotic Gene Conversion	Cytoplasm Cytosol Mitophagy Cellular Response To Nitrogen Starvation Regulation Of Phosphorus Metabolic Process Autophagy Of Mitochondrion Phosphatidylethanolamine Binding Meiotic Spindle Ubiquitin-ubiquitin Ligase Activity Protein Modification Process Regulation Of Glutamate Secretion Sperm DNA Condensation Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Protein K48-linked Ubiquitination Intracellular Signaling Cassette Intracellular Signal Transduction Regulation Of Secretion By Cell Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Ketone Metabolic Process Protein K6-linked Ubiquitination Protein Polyubiquitination Interleukin-5 Receptor Complex Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Protein Catabolic Process Phospholipid Binding Ubiquitin Protein Ligase Binding FMN Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FAD Transmembrane Transport Monoatomic Anion:monoatomic Cation Symporter Activity Protein-N-terminal Glutamine Amidohydrolase Activity
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