SEPTIN1 and SEPTIN9

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SEPTIN1	SEPTIN9
Description		septin 1	septin 9
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Meiotic Spindle	Stress Fiber Cytoplasm Cytoskeleton Microtubule Cilium Axoneme Septin Ring Actin Cytoskeleton Microtubule Cytoskeleton Septin Complex Cell Division Site Intercellular Bridge Perinuclear Region Of Cytoplasm Non-motile Cilium
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Spindle Assembly Involved In Female Meiosis Intracellular Protein Localization Regulation Of Exocytosis Cell Division Meiotic Metaphase Chromosome Alignment Cytoskeleton-dependent Cytokinesis	Intracellular Protein Localization Actin Cytoskeleton Organization Septin Cytoskeleton Organization Cell Division Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly
Pathways
Drugs
Diseases			Hereditary neuralgic amyotrophy (HNA); Hereditary brachial plexus neuropathy
GWAS
Interacting Genes		24 interacting genes: AMOT APP AURKB DDIT4L DNAJB13 GORASP2 GPSM1 HSF2BP LNX1 MID2 MRPL12 NIF3L1 PICK1 PIH1D1 SDCBP SEPTIN11 SEPTIN3 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC UBE2I	21 interacting genes: APP CEBPA HIF1A HNRNPD HSF2BP IKBKG LINC00839 LINC01554 MYO1C MYO6 NEDD4 PIN1 PLK1 PTPRF RAB10 SEPTIN1 SEPTIN11 SEPTIN2 SEPTIN6 SEPTIN7 STK11
Entrez ID		1731	10801
HPRD ID		15324	10360
Ensembl ID		ENSG00000180096	ENSG00000184640
Uniprot IDs		J3KNL2 Q8WYJ6	A0A0S2Z5A5 Q9UHD8
PDB IDs		6WBE	4YQF 5CYO 5CYP
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Molecular Adaptor Activity Microtubule Cytoskeleton Cell Division Cytoplasm GTPase Activity Intracellular Protein Localization Cytoskeleton GTP Binding Regulation Of Receptor Internalization Stress Fiber Synaptonemal Complex Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Synaptic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Frizzled Binding Interleukin-5 Receptor Complex SUMO Conjugating Enzyme Activity Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Phosphoprotein Binding Septin Collar Meiotic Gene Conversion	Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Midbody Sperm Annulus Positive Regulation Of Catabolic Process Microtubule Cytoskeleton GTPase Activity Intracellular Protein Localization Molecular Adaptor Activity Positive Regulation Of Protein Metabolic Process GTP Binding Phosphothreonine Residue Binding Cellular Response To Stress Nucleotide Binding Cell Division Organelle Localization Phosphoserine Residue Binding Unconventional Myosin Complex Cytoskeletal Motor Activity Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus Cleavage Furrow Response To Metal Ion Chromosome, Centromeric Region Kinetochore Cell Cortex Cell Projection Regulation Of Protein Localization Regulation Of Protein Catabolic Process Anoikis Positive Regulation Of Proteolysis Reproductive Process Positive Regulation Of Protein Catabolic Process Motile Cilium Intracellular Signal Transduction Protein Domain Specific Binding Stress Fiber Spindle Cellular Developmental Process Cytoplasm Cell Projection Organization Protein-containing Complex Spermatogenesis Male Gamete Generation Establishment Of Localization In Cell Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Establishment Of Organelle Localization DNA Damage Response
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