SEPTIN1 and PIH1D1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEPTIN1	PIH1D1
Description		septin 1	PIH1 domain containing 1
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Meiotic Spindle	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex RPAP3/R2TP/prefoldin-like Complex Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding Histone Reader Activity
	Biological Process	Spindle Assembly Involved In Female Meiosis Intracellular Protein Localization Regulation Of Exocytosis Cell Division Meiotic Metaphase Chromosome Alignment Cytoskeleton-dependent Cytokinesis	Box C/D SnoRNP Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation SnoRNA Localization Protein Stabilization Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling TORC1 Complex Assembly
Pathways
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: AMOT APP AURKB DDIT4L DNAJB13 GORASP2 GPSM1 HSF2BP LNX1 MID2 MRPL12 NIF3L1 PICK1 PIH1D1 SDCBP SEPTIN11 SEPTIN3 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC UBE2I	19 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4 UBC
Entrez ID		1731	55011
HPRD ID		15324	07938
Ensembl ID		ENSG00000180096	ENSG00000104872
Uniprot IDs		J3KNL2 Q8WYJ6	Q9NWS0
PDB IDs		6WBE	4PSF 4PSI 6GXZ 7AVC 8BDU
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Molecular Adaptor Activity Microtubule Cytoskeleton Cell Division Cytoplasm GTPase Activity Intracellular Protein Localization Cytoskeleton GTP Binding Regulation Of Receptor Internalization Stress Fiber Synaptonemal Complex Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Synaptic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Frizzled Binding Interleukin-5 Receptor Complex SUMO Conjugating Enzyme Activity Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Phosphoprotein Binding Septin Collar Meiotic Gene Conversion
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