ZNF138 and ELOA2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ZNF138	ELOA2
Name		zinc finger protein 138	elongin A2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Elongin Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation
Pathways		Generic Transcription Pathway	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		16 interacting genes: BCCIP DHPS ELOA2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP12-3 LHX6 LMNA MAPK9 MDFI TRIM41 ZBTB8A	23 interacting genes: CALCOCO2 CBX5 CDK6 CEP70 CHD2 COIL DVL2 ELOB ELOC HSF2BP KRTAP4-12 KXD1 NKAPD1 RNPS1 SOHLH2 SREK1IP1 TRAF2 TRIM37 ZBTB43 ZCCHC10 ZNF138 ZNF165 ZNF23
Entrez ID		7697	51224
HPRD ID		07244	18169
Ensembl ID		ENSG00000197008	ENSG00000206181
Uniprot IDs		A0A0A0MRG3 A0A0A0MT90 A2RRP7 C9JHF6 E7EWC5 J3QSS9 P52744	Q8IYF1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament	Target-directed MiRNA Degradation Elongin Complex Protein-macromolecule Adaptor Activity Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Negative Regulation Of MiRNA-mediated Gene Silencing MiRNA Catabolic Process Cul5-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Hematopoietic Stem Cell Differentiation Ubiquitin Ligase Complex MiRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Tumor Necrosis Factor Receptor Binding Aggresome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cyclin D2-CDK6 Complex TORC2 Complex Disassembly RNA Polymerase III General Transcription Initiation Factor Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Initiation At RNA Polymerase II Promoter Transcription Corepressor Binding RNA Catabolic Process Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding