FAM9C and TRIML2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM9C	TRIML2
Description		family with sequence similarity 9 member C	tripartite motif family like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Spermatid Development Meiotic Cell Cycle	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)	Polycystic ovary syndrome ( 25574032)
Interacting Genes		8 interacting genes: ABI2 BORCS6 CFTR SKA1 SNAPC5 TEX12 TPM3 TRIML2	46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3
Entrez ID		171484	205860
HPRD ID		06507	08696
Ensembl ID		ENSG00000187268	ENSG00000179046
Uniprot IDs		Q8IZT9	A0A804HJA0 B7ZLC3 Q8N7C3
PDB IDs
Enriched GO Terms of Interacting Partners?		Bicarbonate Transmembrane Transporter Activity Organelle Localization Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Actin Filament Muscle Thin Filament Tropomyosin Positive Regulation Of Supramolecular Fiber Organization Actin-based Cell Projection Lens Fiber Cell Morphogenesis Zonula Adherens Assembly Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase III Regulation Of Lysosome Size BORC Complex Meiotic DNA Repair Synthesis Central Element Establishment Of Meiotic Spindle Orientation Establishment Of Meiotic Spindle Localization SKA Complex Negative Regulation Of Mitotic Spindle Assembly Checkpoint Signaling	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion
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