FAM9C and BORCS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM9C	BORCS6
Description		family with sequence similarity 9 member C	BLOC-1 related complex subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus	Lysosome Lysosomal Membrane Membrane Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		8 interacting genes: ABI2 BORCS6 CFTR SKA1 SNAPC5 TEX12 TPM3 TRIML2	31 interacting genes: ABI2 AIRIM BEX2 C19orf25 C1orf216 DRC4 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 HAUS1 HGS KANK2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655
Entrez ID		171484	54785
HPRD ID		06507	13368
Ensembl ID		ENSG00000187268	ENSG00000196544
Uniprot IDs		Q8IZT9	Q96GS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Bicarbonate Transmembrane Transporter Activity Organelle Localization Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Actin Filament Muscle Thin Filament Tropomyosin Positive Regulation Of Supramolecular Fiber Organization Actin-based Cell Projection Lens Fiber Cell Morphogenesis Zonula Adherens Assembly Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase III Regulation Of Lysosome Size BORC Complex Meiotic DNA Repair Synthesis Central Element Establishment Of Meiotic Spindle Orientation Establishment Of Meiotic Spindle Localization SKA Complex Negative Regulation Of Mitotic Spindle Assembly Checkpoint Signaling
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