FAM9C and TEX12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM9C	TEX12
Description		family with sequence similarity 9 member C	testis expressed 12
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus	Synaptonemal Complex Central Element Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Meiotic DNA Repair Synthesis Synaptonemal Complex Assembly Meiotic Cell Cycle
Pathways			Meiotic synapsis
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)	Inflammatory biomarkers ( 24182552)
Interacting Genes		8 interacting genes: ABI2 BORCS6 CFTR SKA1 SNAPC5 TEX12 TPM3 TRIML2	19 interacting genes: AIMP2 AP2B1 CCNC CEP57 COX5B FAM161B FAM9C INCA1 LENG1 MESD MSGN1 NUP54 OIP5 PPP1R13B SGF29 SMARCE1 SUOX SYCE2 ZNF835
Entrez ID		171484	56158
HPRD ID		06507	12045
Ensembl ID		ENSG00000187268	ENSG00000150783
Uniprot IDs		Q8IZT9	Q9BXU0
PDB IDs			6HK8 6HK9 6R17 6R2F 6YQF
Enriched GO Terms of Interacting Partners?		Bicarbonate Transmembrane Transporter Activity Organelle Localization Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Actin Filament Muscle Thin Filament Tropomyosin Positive Regulation Of Supramolecular Fiber Organization Actin-based Cell Projection Lens Fiber Cell Morphogenesis Zonula Adherens Assembly Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase III Regulation Of Lysosome Size BORC Complex Meiotic DNA Repair Synthesis Central Element Establishment Of Meiotic Spindle Orientation Establishment Of Meiotic Spindle Localization SKA Complex Negative Regulation Of Mitotic Spindle Assembly Checkpoint Signaling
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