TXLNB and LPXN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TXLNB	LPXN
Description		taxilin beta	leupaxin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	Protein Binding Syntaxin Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process		Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Caudate volume in trauma-exposed individuals ( 29187748) Heel bone mineral density ( 30598549) Non-albumin protein levels ( 29403010) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		67 interacting genes: AXIN2 BTF3 BTF3L4 C18orf54 CAGE1 CBY2 CCDC13 CCDC14 CCDC152 CCDC196 CCDC88B CCHCR1 CDR2 CEP19 CEP57 CEP57L1 CEP70 CFAP53 CT55 DCTN2 DEUP1 DMAP1 DRC4 DYDC1 EXOC5 FAM161A FAM167A GOLGA2 HAUS3 KIAA1328 KRT13 KRT15 KRT16 KRT26 KRT27 KRT34 KRT35 KRT37 KRT38 KRT39 KRT6A KRT75 LPXN LZTS1 MBIP MEOX2 MNS1 NEFL NF2 NMI ODAD3 SIKE1 SNAPC5 SOX13 STMN3 STX1A STX4 TADA3 TCL1A TXLNA UBE2I USHBP1 UTP14A VIM VPS52 WASHC3 ZNF20	33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426
Entrez ID		167838	9404
HPRD ID		10793	05651
Ensembl ID		ENSG00000164440	ENSG00000110031
Uniprot IDs		Q8N3L3	B7Z5P7 O60711
PDB IDs			1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Intermediate Filament Keratin Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytosol Tissue Morphogenesis Protein Binding Microtubule Cytoskeleton Organization Microtubule-based Process Cell Projection Cilium Organization Anatomical Structure Morphogenesis Centrosome Centriole Structural Constituent Of Cytoskeleton Cilium Sperm Flagellum Mitotic Spindle Ciliary Basal Body Gamma-tubulin Binding Polymeric Cytoskeletal Fiber Identical Protein Binding Microtubule Binding Cell Differentiation Plasma Membrane Bounded Cell Projection Organization Microtubule Organizing Center Cilium Assembly Schaffer Collateral - CA1 Synapse Epithelial Cilium Movement Involved In Extracellular Fluid Movement Osteoblast Proliferation Extracellular Transport Syntaxin Binding Intermediate Filament Cytoskeleton Cell Projection Organization SNARE Complex Assembly Flagellated Sperm Motility Negative Regulation Of Osteoblast Proliferation Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Motility Exocytosis Axoneme	Response To Dexamethasone Focal Adhesion Positive Regulation Of Fibroblast Migration Developmental Growth Developmental Growth Involved In Morphogenesis Anchoring Junction Cellular Response To Dexamethasone Stimulus Cellular Response To Lipid Cellular Response To Oxygen-containing Compound Multicellular Organismal-level Homeostasis Positive Regulation Of Mononuclear Cell Migration Regulation Of Fibroblast Migration Response To Fluid Shear Stress Developmental Cell Growth Response To Lipid Signal Complex Assembly Regulation Of Cell-matrix Adhesion Response To Glucocorticoid Regulation Of Fat Cell Differentiation Cellular Response To Glucocorticoid Stimulus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Cellular Response To Growth Factor Stimulus Response To Corticosteroid Regulation Of RNA Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Corticosteroid Stimulus Anatomical Structure Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Focal Adhesion Assembly Regulation Of RNA Biosynthetic Process Response To Growth Factor Response To Transforming Growth Factor Beta Negative Regulation Of Nucleobase-containing Compound Metabolic Process ERBB Signaling Pathway Regulation Of Cell-substrate Junction Organization MAP Kinase Activity Regulation Of Primary Metabolic Process Regulation Of Cytoskeleton Organization Cellular Response To Steroid Hormone Stimulus Nucleus Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Neuron Projection Extension Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Migration Positive Regulation Of Catabolic Process Response To Wounding
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