TXLNB and SIKE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXLNB	SIKE1
Description		taxilin beta	suppressor of IKBKE 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Cytosol FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Small GTPase Binding
	Biological Process		Negative Regulation Of Hippo Signaling
Pathways			TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Caudate volume in trauma-exposed individuals ( 29187748) Heel bone mineral density ( 30598549) Non-albumin protein levels ( 29403010) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age at first sexual intercourse ( 34211149)
Interacting Genes		67 interacting genes: AXIN2 BTF3 BTF3L4 C18orf54 CAGE1 CBY2 CCDC13 CCDC14 CCDC152 CCDC196 CCDC88B CCHCR1 CDR2 CEP19 CEP57 CEP57L1 CEP70 CFAP53 CT55 DCTN2 DEUP1 DMAP1 DRC4 DYDC1 EXOC5 FAM161A FAM167A GOLGA2 HAUS3 KIAA1328 KRT13 KRT15 KRT16 KRT26 KRT27 KRT34 KRT35 KRT37 KRT38 KRT39 KRT6A KRT75 LPXN LZTS1 MBIP MEOX2 MNS1 NEFL NF2 NMI ODAD3 SIKE1 SNAPC5 SOX13 STMN3 STX1A STX4 TADA3 TCL1A TXLNA UBE2I USHBP1 UTP14A VIM VPS52 WASHC3 ZNF20	13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C
Entrez ID		167838	80143
HPRD ID		10793	07958
Ensembl ID		ENSG00000164440	ENSG00000052723
Uniprot IDs		Q8N3L3	Q9BRV8
PDB IDs			6AKK 6AKL 6AKM
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Intermediate Filament Keratin Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytosol Tissue Morphogenesis Protein Binding Microtubule Cytoskeleton Organization Microtubule-based Process Cell Projection Cilium Organization Anatomical Structure Morphogenesis Centrosome Centriole Structural Constituent Of Cytoskeleton Cilium Sperm Flagellum Mitotic Spindle Ciliary Basal Body Gamma-tubulin Binding Polymeric Cytoskeletal Fiber Identical Protein Binding Microtubule Binding Cell Differentiation Plasma Membrane Bounded Cell Projection Organization Microtubule Organizing Center Cilium Assembly Schaffer Collateral - CA1 Synapse Epithelial Cilium Movement Involved In Extracellular Fluid Movement Osteoblast Proliferation Extracellular Transport Syntaxin Binding Intermediate Filament Cytoskeleton Cell Projection Organization SNARE Complex Assembly Flagellated Sperm Motility Negative Regulation Of Osteoblast Proliferation Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Motility Exocytosis Axoneme	TRNA Threonylcarbamoyladenosine Metabolic Process Positive Regulation Of Type I Interferon-mediated Signaling Pathway Serine/threonine Protein Kinase Complex Type I Interferon-mediated Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway Protein-N-terminal Glutamine Amidohydrolase Activity Syntaxin Binding Positive Regulation Of Cytokine-mediated Signaling Pathway Interferon-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Protein Localization To Kinetochore
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