CCDC116 and ZMYND12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC116	ZMYND12
Description		coiled-coil domain containing 116	zinc finger MYND-type containing 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process		Sperm Axoneme Assembly Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: AKAP9 BEX3 CARD10 CCDC85B CDCA7L CEP20 CEP44 COG6 CSNK2A1 CTAG1A CTAG1B FAM9B GOLGA6L9 HSF2BP IGFBP6 KRT31 KRT40 KRTAP4-12 MDFI MEIS3 MTUS2 NUTM1 PKNOX2 PPP1R16A RASSF10 SLC2A4 TADA2A TFIP11 TRAF1 USHBP1 ZMYND12 ZNF655	80 interacting genes: ABI2 AIRIM ARHGAP8 ARMC8 ATOSB BMAL1 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SAXO4 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414
Entrez ID		164592	84217
HPRD ID		08203	15740
Ensembl ID		ENSG00000161180	ENSG00000066185
Uniprot IDs		Q8IYX3	B4DX70 Q9H0C1
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?			Protein Binding Sperm Flagellum Axonemal A Tubule Inner Sheath Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Motile Cilium Regulation Of RNA Metabolic Process Nucleus Chromatin Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Transcription Coregulator Activity
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