CCDC116 and CEP20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC116	CEP20
Description		coiled-coil domain containing 116	centrosomal protein 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Nucleoplasm Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Cilium Motile Cilium Centriolar Satellite Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Cell Projection Organization Microtubule Anchoring Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: AKAP9 BEX3 CARD10 CCDC85B CDCA7L CEP20 CEP44 COG6 CSNK2A1 CTAG1A CTAG1B FAM9B GOLGA6L9 HSF2BP IGFBP6 KRT31 KRT40 KRTAP4-12 MDFI MEIS3 MTUS2 NUTM1 PKNOX2 PPP1R16A RASSF10 SLC2A4 TADA2A TFIP11 TRAF1 USHBP1 ZMYND12 ZNF655	8 interacting genes: CCDC116 S100A1 S100A11 S100A2 S100A4 S100A6 S100B TUBA1A
Entrez ID		164592	123811
HPRD ID		08203	08096
Ensembl ID		ENSG00000161180	ENSG00000133393
Uniprot IDs		Q8IYX3	I3L269 I3L2N4 I3L4V2 I3NI25 Q96NB1
PDB IDs
Enriched GO Terms of Interacting Partners?			Calcium-dependent Protein Binding S100 Protein Binding Calcium Ion Binding RAGE Receptor Binding Ruffle Identical Protein Binding Transition Metal Ion Binding Metal Ion Binding Protein Homodimerization Activity Neuron Projection Morphogenesis Cell Projection Morphogenesis Extracellular Region Glial Cell Differentiation Memory Axonogenesis Pyramidal Neuron Differentiation Cerebellar Cortex Morphogenesis Response To Anesthetic Response To Methylmercury Sympathetic Neuron Projection Extension
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