DDB1 and SUPT3H

Number of citations of the paper that reports this interaction (PMID 11564863)
111

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		DDB1	SUPT3H
Gene Name		damage-specific DNA binding protein 1, 127kDa	suppressor of Ty 3 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cul4A-RING E3 Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Vesicular Exosome Cul4-RING E3 Ubiquitin Ligase Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Damaged DNA Binding Protein Binding	DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Heterodimerization Activity
	Biological Process	Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Viral Process Wnt Signaling Pathway Histone H2A Monoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Interaction With Symbiont UV-damage Excision Repair Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Viral Release From Host Cell	Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Histone Deubiquitination Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER Dual incision reaction in GG-NER	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Bone mineral density ( 22504420) Height ( 19893584 23563607 18391951) Obesity-related traits ( 23251661) Osteoarthritis ( 22763110) Stroke (ischemic) ( 22941190)
Protein-Protein Interactions		40 interactors: ABL1 BRAP CDT1 CNOT2 COPS2 COPS5 COPS8 CUL4A CUL4B DCAF11 DCAF8 DCLRE1C DDB2 DET1 DTL DYRK2 ERCC8 GPS1 HIST1H1C HIST1H3A HOXD3 IP6K1 LMO4 MAFB MEF2A PIN1 RASSF1 RBX1 SALL2 SIN3A SKP2 STAT1 SUPT3H TP53 UNG USP40 VAMP3 WDTC1 XPA ZNF277	5 interactors: DDB1 HIST3H3 MYC PYGO2 TCF3
Entrez ID		1642	8464
HPRD ID		10952	04254
Ensembl ID		ENSG00000167986	ENSG00000196284
Uniprot IDs		Q16531	B4E1H0 O75486
PDB IDs		2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4E54 4E5Z
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Cellular Metabolic Process Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cullin Deneddylation Nucleobase-containing Compound Metabolic Process Protein Ubiquitination DNA Repair Protein Deneddylation Heterocycle Metabolic Process Protein Modification By Small Protein Conjugation Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Regulation Of Cell Cycle Protein Modification By Small Protein Removal Nitrogen Compound Metabolic Process Response To UV Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Metabolic Process Protein Monoubiquitination Immune System Development Cellular Response To Stimulus Metabolic Process Catabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Cycle Response To Radiation Regulation Of Cellular Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Process Regulation Of Cell Cycle Process Intrinsic Apoptotic Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Light Stimulus Nucleotide-excision Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Nitrogen Compound Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Protein Metabolic Process Cellular Protein Catabolic Process Embryo Development Ending In Birth Or Egg Hatching	Wnt Signaling Pathway Canonical Wnt Signaling Pathway Chromosome Organization Organelle Organization Cellular Response To UV Cellular Response To Light Stimulus Chromatin Modification Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Chromatin Organization Response To UV Cellular Response To Radiation Fibroblast Apoptotic Process Regulation Of Cell Cycle Positive Regulation By Virus Of Viral Protein Levels In Host Cell Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Chromosome Organization DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Chromatin Binding Axial Mesoderm Morphogenesis Negative Regulation Of Monocyte Differentiation Immunoglobulin V(D)J Recombination UV-damage Excision Repair Positive Regulation Of Cell Proliferation Involved In Kidney Development Cell Surface Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Positive Regulation Of Viral Release From Host Cell Kidney Development Homeostatic Process Renal System Development Axial Mesoderm Development Response To Light Stimulus B Cell Lineage Commitment Regulation Of Cell Proliferation Histone H2A Monoubiquitination Urogenital System Development Histone Modification Regulation Of Mitotic Cell Cycle Regulation Of Monocyte Differentiation Peyer's Patch Development Histone H2A Ubiquitination Response To Radiation Regulation Of Mammary Gland Epithelial Cell Proliferation Natural Killer Cell Differentiation Nucleotide-excision Repair, DNA Damage Removal Regulation Of Telomere Maintenance Anterior/posterior Axis Specification, Embryo Regulation Of Cell Cycle Process Positive Regulation Of DNA Biosynthetic Process
Tagcloud ?		accordingly adaptor arabidopsis atgenexpress crl4 cullin4 dhu1 doses downregulated dwd e3 exhibits hypersensitive hypersensitivity hypocotyl hypocotyls illumination implying insertion ligase mumol named responsiveness substrate times ultraviolet upregulated uv visualization
Tagcloud (Difference) ?		accordingly adaptor arabidopsis atgenexpress crl4 cullin4 dhu1 doses downregulated dwd e3 exhibits hypersensitive hypersensitivity hypocotyl hypocotyls illumination implying insertion ligase mumol named responsiveness substrate times ultraviolet upregulated uv visualization
Tagcloud (Intersection) ?