SUPT3H

Gene Name		suppressor of Ty 3 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Heterodimerization Activity
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Histone Deubiquitination Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Bone mineral density ( 22504420) Height ( 19893584 23563607 18391951) Obesity-related traits ( 23251661) Osteoarthritis ( 22763110) Stroke (ischemic) ( 22941190)
Protein-protein Interactions		5 interactors: DDB1 HIST3H3 MYC PYGO2 TCF3
Entrez ID		8464
HPRD ID		04254
Ensembl ID		ENSG00000196284
Uniprot IDs		B4E1H0 O75486
PDB IDs
Enriched GO Terms of Interacting Partners?		Wnt Signaling Pathway Canonical Wnt Signaling Pathway Chromosome Organization Organelle Organization Cellular Response To UV Cellular Response To Light Stimulus Chromatin Modification Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Chromatin Organization Response To UV Cellular Response To Radiation Fibroblast Apoptotic Process Regulation Of Cell Cycle Positive Regulation By Virus Of Viral Protein Levels In Host Cell Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Chromosome Organization DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Chromatin Binding Axial Mesoderm Morphogenesis Negative Regulation Of Monocyte Differentiation Immunoglobulin V(D)J Recombination UV-damage Excision Repair Positive Regulation Of Cell Proliferation Involved In Kidney Development Cell Surface Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Positive Regulation Of Viral Release From Host Cell Kidney Development Homeostatic Process Renal System Development Axial Mesoderm Development Response To Light Stimulus B Cell Lineage Commitment Regulation Of Cell Proliferation Histone H2A Monoubiquitination Urogenital System Development Histone Modification Regulation Of Mitotic Cell Cycle Regulation Of Monocyte Differentiation Peyer's Patch Development Histone H2A Ubiquitination Response To Radiation Regulation Of Mammary Gland Epithelial Cell Proliferation Natural Killer Cell Differentiation Nucleotide-excision Repair, DNA Damage Removal Regulation Of Telomere Maintenance Anterior/posterior Axis Specification, Embryo Regulation Of Cell Cycle Process Positive Regulation Of DNA Biosynthetic Process
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