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SUPT3H
Description
SPT3 homolog, SAGA and STAGA complex component
Image
GO Annotations
Cellular Component
SAGA Complex
Nucleus
Nucleoplasm
Transcription Factor TFTC Complex
Molecular Function
Transcription Coactivator Activity
Protein Heterodimerization Activity
Biological Process
Regulation Of DNA Repair
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Regulation Of RNA Splicing
Positive Regulation Of DNA-templated Transcription
Pathways
HATs acetylate histones
Drugs
Diseases
GWAS
ADAMTS13 activity (
25934476
)
Appendicular lean mass (
33097823
)
Attention deficit hyperactivity disorder (
18839057
)
Chin dimples (
27182965
)
Estimated glomerular filtration rate (
31152163
)
facial morphology traits (multivariate analysis) (
27193062
)
Glaucoma (
31959993
)
Heel bone mineral density (
30598549
28869591
)
Height (
23563607
31562340
28552196
18391951
25429064
19893584
25282103
)
Hip circumference adjusted for BMI (
34021172
)
Hip minimal joint space width (
27701424
)
Intraocular pressure (
31959993
30054594
)
Large artery stroke (
24262325
)
Lumbar spine bone mineral density (
22504420
)
Lymphocyte count (
32888494
)
Male-pattern baldness (
27182965
)
Monobrow (
27182965
)
Nose morphology (
29921221
)
Nose size (
27182965
)
Obesity-related traits (
23251661
)
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder (
27021288
)
Ossification of the posterior longitudinal ligament of the spine (
25064007
)
Osteoarthritis (
22763110
)
Osteoarthritis of the hand (
28855172
)
Osteoarthritis of the hip or knee (
30664745
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Serum alkaline phosphatase levels (
33547301
)
Stroke (ischemic) (
22941190
)
Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder (
33824429
)
Waist circumference adjusted for body mass index (
34021172
)
Interacting Genes
5 interacting genes:
DDB1
H3-4
MYC
PYGO2
TCF3
Entrez ID
8464
HPRD ID
04254
Ensembl ID
ENSG00000196284
Uniprot IDs
B4E1H0
O75486
PDB IDs
7KTR
7KTS
8H7G
Enriched GO Terms of Interacting Partners
?
Wnt Signaling Pathway
Cellular Response To UV
E-box Binding
Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation
Acinar Cell Proliferation
Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Acinar Cell Proliferation
Euchromatin
SCF Ubiquitin Ligase Complex Binding
Cellular Response To Light Stimulus
Nucleoplasm
Response To UV
Regulation Of Cell Cycle Process
Chromatin Remodeling
Cellular Response To Radiation
Protein-containing Complex
DNA Binding
Chromatin Organization
Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Chromosome, Telomeric Region
NK T Cell Proliferation
Myc-Max Complex
Regulation Of Acinar Cell Proliferation
Protein Dimerization Activity
Positive Regulation Of B Cell Apoptotic Process
DNA-binding Transcription Factor Binding
Vitamin D Response Element Binding
Spermatogonial Cell Division
Histone Acetyltransferase Regulator Activity
Base-excision Repair, AP Site Formation Via Deaminated Base Removal
WD40-repeat Domain Binding
Cul4B-RING E3 Ubiquitin Ligase Complex
Regulation Of Developmental Process
Negative Regulation Of DNA-templated Transcription Initiation
Negative Regulation Of Transcription Initiation By RNA Polymerase II
Negative Regulation Of Monocyte Differentiation
B Cell Lineage Commitment
DNA Replication-dependent Chromatin Assembly
Ubiquitin Ligase Complex Scaffold Activity
Regulation Of Cell Cycle
RNA Polymerase II Transcription Repressor Complex
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Immunoglobulin V(D)J Recombination
Epigenetic Regulation Of Gene Expression
NK T Cell Activation
Positive Regulation Of Cell Proliferation Involved In Kidney Development
Negative Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Kidney Development
Cellular Response To Interferon-alpha
Tagcloud
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