DDB1 and UNG

Number of citations of the paper that reports this interaction (PMID 20870715)
26

Data Source:
BioGRID (pull down)

		DDB1	UNG
Gene Name		damage-specific DNA binding protein 1, 127kDa	uracil-DNA glycosylase
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cul4A-RING E3 Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Vesicular Exosome Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	DNA Binding Damaged DNA Binding Protein Binding	Uracil DNA N-glycosylase Activity Protein Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Viral Process Wnt Signaling Pathway Histone H2A Monoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Interaction With Symbiont UV-damage Excision Repair Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Viral Release From Host Cell	DNA Repair Base-excision Repair Base-excision Repair, AP Site Formation Viral Process Somatic Hypermutation Of Immunoglobulin Genes Somatic Recombination Of Immunoglobulin Gene Segments Negative Regulation Of Apoptotic Process Depyrimidination
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: ABL1 BRAP CDT1 CNOT2 COPS2 COPS5 COPS8 CUL4A CUL4B DCAF11 DCAF8 DCLRE1C DDB2 DET1 DTL DYRK2 ERCC8 GPS1 HIST1H1C HIST1H3A HOXD3 IP6K1 LMO4 MAFB MEF2A PIN1 RASSF1 RBX1 SALL2 SIN3A SKP2 STAT1 SUPT3H TP53 UNG USP40 VAMP3 WDTC1 XPA ZNF277	7 interactors: APP CAPN11 DDB1 PCNA RPA2 SEZ6L2 VPRBP
Entrez ID		1642	7374
HPRD ID		10952	01881
Ensembl ID		ENSG00000167986	ENSG00000076248
Uniprot IDs		Q16531	E5KTA5 E5KTA6 P13051
PDB IDs		2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4E54 4E5Z	1AKZ 1DPU 1EMH 1EMJ 1Q3F 1SSP 1UGH 1YUO 2HXM 2OXM 2OYT 2SSP 3FCF 3FCI 3FCK 3FCL 3TKB 4SKN
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Cellular Metabolic Process Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cullin Deneddylation Nucleobase-containing Compound Metabolic Process Protein Ubiquitination DNA Repair Protein Deneddylation Heterocycle Metabolic Process Protein Modification By Small Protein Conjugation Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Regulation Of Cell Cycle Protein Modification By Small Protein Removal Nitrogen Compound Metabolic Process Response To UV Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Metabolic Process Protein Monoubiquitination Immune System Development Cellular Response To Stimulus Metabolic Process Catabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Cycle Response To Radiation Regulation Of Cellular Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Process Regulation Of Cell Cycle Process Intrinsic Apoptotic Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Light Stimulus Nucleotide-excision Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Nitrogen Compound Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Protein Metabolic Process Cellular Protein Catabolic Process Embryo Development Ending In Birth Or Egg Hatching	Nucleotide-excision Repair Nucleotide-excision Repair, DNA Gap Filling Nucleotide-excision Repair, DNA Damage Removal Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition DNA Recombination Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Transcription-coupled Nucleotide-excision Repair Chromosome Organization DNA Metabolic Process Regulation Of Mitotic Cell Cycle Mismatch Repair Base-excision Repair Homeostatic Process Telomere Maintenance Regulation Of Cell Cycle Process Cell Competition In A Multicellular Organism Positive Regulation Of Deoxyribonuclease Activity Histone H2A-T120 Phosphorylation DNA-dependent DNA Replication DNA Repair Cellular Homeostasis Leading Strand Elongation Synaptic Growth At Neuromuscular Junction DNA Catabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation By Virus Of Viral Protein Levels In Host Cell Collateral Sprouting In Absence Of Injury Cellular Response To DNA Damage Stimulus Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition DNA Recombinase Assembly Nucleobase-containing Compound Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition UV-damage Excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Cell Cycle Phase Transition Positive Regulation Of Viral Release From Host Cell DNA Replication
Tagcloud ?		accordingly adaptor arabidopsis atgenexpress crl4 cullin4 dhu1 doses downregulated dwd e3 exhibits hypersensitive hypersensitivity hypocotyl hypocotyls illumination implying insertion ligase mumol named responsiveness substrate times ultraviolet upregulated uv visualization	choe collided colonial communism communist cooperatives defected defection faction heath ideologies imagination instatement laborers liberation nationalization pharmaceutics politics pyongyang reeducation respite socialism socialist sok soviet stood symbolically unions usamgik
Tagcloud (Difference) ?		accordingly adaptor arabidopsis atgenexpress crl4 cullin4 dhu1 doses downregulated dwd e3 exhibits hypersensitive hypersensitivity hypocotyl hypocotyls illumination implying insertion ligase mumol named responsiveness substrate times ultraviolet upregulated uv visualization	choe collided colonial communism communist cooperatives defected defection faction heath ideologies imagination instatement laborers liberation nationalization pharmaceutics politics pyongyang reeducation respite socialism socialist sok soviet stood symbolically unions usamgik
Tagcloud (Intersection) ?