DEDD and GTF3C3

Number of citations of the paper that reports this interaction (PMID 11965497)
8

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		DEDD	GTF3C3
Gene Name		death effector domain containing	general transcription factor IIIC, polypeptide 3, 102kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Transcription, DNA-templated Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 KRT18 KRT8 SHMT1 SMAD3	7 interactors: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP
Entrez ID		9191	9330
HPRD ID		06022	11997
Ensembl ID		ENSG00000158796	ENSG00000119041
Uniprot IDs		B1AQP5 B4DKM1 O75618	Q9Y5Q9
PDB IDs
Enriched GO Terms of Interacting Partners?		Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Peptidase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Endopeptidase Activity Activation Of Cysteine-type Endopeptidase Activity Regulation Of Peptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Proteolysis Regulation Of Proteolysis Hepatocyte Apoptotic Process Regulation Of Necroptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Processing Regulation Of Necrotic Cell Death Viral Process TRAIL-activated Apoptotic Signaling Pathway Response To Tumor Necrosis Factor Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Regulation Of Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Apoptotic Signaling Pathway Neuron Apoptotic Process TRNA Transcription Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Neuron Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Execution Phase Of Apoptosis Negative Regulation Of Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Cell Death Positive Regulation Of Macrophage Differentiation Negative Regulation Of Necroptotic Process Positive Regulation Of Hydrolase Activity	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase III Promoter RNA Metabolic Process TRNA Transcription Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Aromatic Compound Catabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Catabolic Process Biosynthetic Process RRNA Transcription Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Extrinsic Apoptotic Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Proepicardium Development Catabolic Process Placenta Development Cellular Macromolecule Catabolic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Circadian Regulation Of Translation DNA-templated Transcription, Initiation Apoptotic Process Programmed Cell Death Transcription Initiation From RNA Polymerase III Promoter Cell Death Death Tetrahydrobiopterin Biosynthetic Process Cellular Metabolic Process Regulation Of Translation Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RRNA Catabolic Process L-phenylalanine Catabolic Process
Tagcloud ?		actinobacteria cleaving detectable distant divergent duplex equivalent exoribonuclease founding homology hundreds hypothetical kingdom maintain mediating orthologs overhangs pathogen phylogenetically pool prevalent proteobacteria reveals ribonucleases rnase rnases rv2179c similarity strand
Tagcloud (Difference) ?		actinobacteria cleaving detectable distant divergent duplex equivalent exoribonuclease founding homology hundreds hypothetical kingdom maintain mediating orthologs overhangs pathogen phylogenetically pool prevalent proteobacteria reveals ribonucleases rnase rnases rv2179c similarity strand
Tagcloud (Intersection) ?