DAG1 and DRP2

Number of citations of the paper that reports this interaction (PMID 11430802)
23

Data Source:
HPRD (in vivo, two hybrid)

		DAG1	DRP2
Gene Name		dystroglycan 1 (dystrophin-associated glycoprotein 1)	dystrophin related protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Adherens Junction Focal Adhesion Cell Outer Membrane Dystrophin-associated Glycoprotein Complex Dystroglycan Complex Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium Filopodium Node Of Ranvier Sarcolemma Costamere Membrane Raft Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Cytoplasm Cytoskeleton Plasma Membrane
	Molecular Function	Virus Receptor Activity Dystroglycan Binding Actin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Tubulin Binding Vinculin Binding Protein Complex Binding SH2 Domain Binding Laminin-1 Binding Alpha-actinin Binding	Zinc Ion Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Membrane Protein Ectodomain Proteolysis NLS-bearing Protein Import Into Nucleus Cytoskeletal Anchoring At Plasma Membrane Response To Virus Calcium-dependent Cell-matrix Adhesion Modulation By Virus Of Host Morphology Or Physiology Nerve Maturation Myelination In Peripheral Nervous System Extracellular Matrix Organization Negative Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of MAPK Cascade Response To Peptide Hormone Negative Regulation Of Protein Kinase B Signaling Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Commissural Neuron Axon Guidance Basement Membrane Organization	Central Nervous System Development
Pathways		ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: AGR2 AGR3 AGRN BGN CAV1 CAV3 DMD DRP2 FYN GRB2 ITGB1 LAMA1 LAMA2 LAMA5 MAGI1 MAP2 NCK1 RAPSN SHC1 SRC TLN1 TUBA1A UTRN WWP1 WWP2	4 interactors: DAG1 DTNA PRX UTRN
Entrez ID		1605	1821
HPRD ID		00546	02083
Ensembl ID		ENSG00000173402	ENSG00000102385
Uniprot IDs		Q14118	Q13474
PDB IDs		1EG4
Enriched GO Terms of Interacting Partners?		Locomotion Regulation Of Cell Adhesion Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Axon Development Axon Guidance Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis System Development Neuron Projection Morphogenesis Cell Projection Organization Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Multicellular Organismal Development Positive Regulation Of Cell Adhesion Neuron Projection Development Anatomical Structure Development Cell Development Chemotaxis Negative Regulation Of Peptidyl-serine Phosphorylation Neuron Development Receptor Metabolic Process Developmental Process Extracellular Matrix Organization Extracellular Structure Organization Neuron Differentiation Regulation Of Body Fluid Levels Nervous System Development Leukocyte Migration Wound Healing Cell Adhesion Cell Differentiation Generation Of Neurons Blood Coagulation Hemostasis Neurogenesis Regulation Of Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Response To Wounding Muscle Organ Development Regulation Of Transmembrane Transporter Activity Negative Regulation Of Anoikis Muscle Structure Development Regulation Of Sodium Ion Transport Regulation Of Protein Phosphorylation Regulation Of Anoikis Regulation Of Phosphorus Metabolic Process Cytoskeleton Organization	Nerve Maturation Axon Ensheathment Calcium-dependent Cell-matrix Adhesion Muscle Contraction Muscle System Process Commissural Neuron Axon Guidance Cytoskeletal Anchoring At Plasma Membrane Basement Membrane Organization Membrane Protein Ectodomain Proteolysis NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Morphology Or Physiology Neuromuscular Synaptic Transmission Branching Involved In Salivary Gland Morphogenesis Regulation Of Sodium Ion Transmembrane Transporter Activity Membrane Protein Proteolysis Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Kinase B Signaling Salivary Gland Morphogenesis Viral Entry Into Host Cell Myelination In Peripheral Nervous System Salivary Gland Development Epithelial Tube Branching Involved In Lung Morphogenesis Entry Into Host Cell Schwann Cell Development Exocrine System Development Positive Regulation Of Cell-matrix Adhesion Morphogenesis Of An Epithelial Sheet Microtubule Anchoring Schwann Cell Differentiation Lung Morphogenesis Regulation Of Sodium Ion Transport
Tagcloud ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	adapter add alpha1 axonal caspr1 cooh disk dystrophin ezrin homology localize map1 map1a map1b map1s maps microtubule multigene occludens paranodin pdz ph2 pleckstrin postsynaptic ranvier schwann sciatic syntrophin zonula
Tagcloud (Difference) ?		branches compensates dag1gai dag1rga28 della dof dormancy embryo factor3 ga ga1 gai germination germination1 insensitive lethal master overlapping phytocrome pil5 repressor rga rga28 seed seeds severely surprisingly t6 unexpected	adapter add alpha1 axonal caspr1 cooh disk dystrophin ezrin homology localize map1 map1a map1b map1s maps microtubule multigene occludens paranodin pdz ph2 pleckstrin postsynaptic ranvier schwann sciatic syntrophin zonula
Tagcloud (Intersection) ?