NKX2-3 and GTF2A1L

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		NKX2-3	GTF2A1L
Gene Name		NK2 homeobox 3	general transcription factor IIA, 1-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus	Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	Molecular_function Sequence-specific DNA Binding	DNA Binding Transcription Coactivator Activity
	Biological Process	Leukocyte Homeostasis Plasma Cell Differentiation Transcription, DNA-templated Triglyceride Metabolic Process Biological_process Gland Morphogenesis Macrophage Differentiation Regulation Of Cell Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cognition
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Inflammatory bowel disease ( 23128233) Red blood cell traits ( 23222517) Ulcerative colitis ( 20228798 20228799)	Polycystic ovary syndrome ( 21151128)
Protein-Protein Interactions		3 interactors: GTF2A1L SRF ZNF212	25 interactors: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3
Entrez ID		159296	11036
HPRD ID		05992	05640
Ensembl ID		ENSG00000119919	ENSG00000242441
Uniprot IDs		Q8TAU0	Q9UNN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Contractile Actin Filament Bundle Assembly Negative Regulation Of Beta-amyloid Clearance Cognition Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription By Glucose Regulation Of Beta-amyloid Clearance Cardiac Vascular Smooth Muscle Cell Differentiation Regulation Of Transcription By Glucose Tangential Migration From The Subventricular Zone To The Olfactory Bulb Transcription, DNA-templated Carbon Catabolite Regulation Of Transcription RNA Biosynthetic Process Dorsal Aorta Morphogenesis Dorsal Aorta Development Positive Thymic T Cell Selection Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Primitive Streak Formation MRNA Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Cardiac Muscle Cell Myoblast Differentiation Stress Fiber Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter MRNA Transcription Positive Regulation Of Transcription Via Serum Response Element Binding Coronary Vasculature Development Cardioblast Differentiation Megakaryocyte Development Heart Trabecula Formation Long Term Synaptic Depression Eyelid Development In Camera-type Eye Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Smooth Muscle Cell Differentiation Angiogenesis Involved In Wound Healing Vascular Smooth Muscle Cell Differentiation Regulation Of Water Loss Via Skin Epithelial Structure Maintenance RNA Metabolic Process Cell Migration Involved In Sprouting Angiogenesis Platelet Formation Platelet Morphogenesis Regulation Of DNA-templated Transcription, Initiation Thymic T Cell Selection Megakaryocyte Differentiation Cardiac Myofibril Assembly Gene Expression Aorta Morphogenesis Trophectodermal Cell Differentiation Muscle Cell Cellular Homeostasis Positive Regulation Of Smooth Muscle Contraction	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Multicellular Organismal Development System Development Anatomical Structure Development Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Embryo Development Cell Differentiation Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Organ Development Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Organ Morphogenesis Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Generation Of Neurons Positive Regulation Of Cellular Metabolic Process Neurogenesis Cerebral Cortex Regionalization Positive Regulation Of Metabolic Process Neuron Differentiation Telencephalon Regionalization Pattern Specification Process Regulation Of Cell Differentiation Embryonic Organ Development Anterior/posterior Pattern Specification
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