REEP6 and SYT16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REEP6	SYT16
Description		receptor accessory protein 6	synaptotagmin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Phospholipid Binding Identical Protein Binding
	Biological Process	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Chronotype ( 30696823) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Hepatitis ( 25705159) Longevity (90 years and older) ( 24688116) Recurrence of mild malaria attacks ( 31667592) Self-rated health ( 20707712) Telomere length ( 24478790)
Interacting Genes		46 interacting genes: AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMPPE TNS2 TXN2 WIPI2 ZFYVE21	29 interacting genes: AGTRAP APOC1 APOC2 APOC4 C10orf67 CMTM5 CYSTM1 DERL3 FGF14 GSG1 HIGD1C LDAF1 MPC2 MTFR1 NCOA5 PHC2 PLEKHF2 RABAC1 REEP6 RER1 RHBDD2 RPRM RTN4 SDR16C5 SFT2D1 SYT14 TMEM239 TVP23B ZBTB14
Entrez ID		92840	83851
HPRD ID		16629	15461
Ensembl ID		ENSG00000115255	ENSG00000139973
Uniprot IDs		A0A1L5BXV2 Q96HR9	Q17RD7
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane	High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Acylglycerol Homeostasis Triglyceride Homeostasis Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Signal Recognition Particle Binding Endoplasmic Reticulum Lipid Homeostasis Chylomicron Phospholipid Efflux Endoplasmic Reticulum Membrane Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Cholesterol Efflux Plasma Lipoprotein Particle Remodeling Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Phosphatidylcholine Catabolic Process Membrane Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process
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