RNF5 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNF5	RABAC1
Description		ring finger protein 5	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Response To Bacterium Negative Regulation Of Autophagy Protein Ubiquitination Protein Catabolic Process Protein Destabilization ERAD Pathway Transmembrane Transport Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Endoplasmic Reticulum Mannose Trimming Regulation Of Autophagosome Assembly
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC) AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Prostate cancer ( 23535732) Soluble receptor for advanced glycation end-product levels ( 26083729) Ulcerative colitis ( 28067908) Waist circumference ( 31453325) Waist circumference variance ( 31453325)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		54 interacting genes: ABHD16A ARL6IP1 CFTR CYB561 CYB561A3 DGAT2L6 EPHA2 EPHA3 EPHA4 FAM241B FHOD1 GLP1R INSIG2 JKAMP JMJD6 LEPROTL1 MPDZ MS4A1 ORMDL3 PGAM5 PLP2 PLPP6 PRAF2 PXN RABAC1 RHBDD1 RUSF1 SCD SEC22A SLC1A1 SLC38A7 TGFBR1 TMEM120B TMEM242 TNFAIP3 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G2 UBE2K UBE2N UBE2U UBE2V1 UBE2W UBE2Z UBTD1 YIPF1 YIPF2 YIPF4	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		6048	10567
HPRD ID		04057	05375
Ensembl ID		ENSG00000204308	ENSG00000105404
Uniprot IDs		A0A024RCQ4 Q99942	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Modification Process Proteolysis Involved In Protein Catabolic Process Protein Monoubiquitination ATP Binding Modification-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Macromolecule Catabolic Process Transferase Activity Ubiquitin-dependent Protein Catabolic Process Protein Binding Proteolysis Nucleotide Binding Protein K63-linked Ubiquitination Protein Metabolic Process Fasciculation Of Motor Neuron Axon Ephrin Receptor Activity Catabolic Process Membrane Positive Regulation Of Protein Polyubiquitination Fasciculation Of Sensory Neuron Axon UBC13-MMS2 Complex ISG15 Transferase Activity Ubiquitin Conjugating Enzyme Complex Cellular Response To Stress Endoplasmic Reticulum Membrane Regulation Of Protein Polyubiquitination Endosome Proteasomal Protein Catabolic Process ISG15-protein Conjugation Cholesterol Biosynthetic Process GPI-linked Ephrin Receptor Activity Positive Regulation Of Protein K63-linked Ubiquitination Golgi Trans Cisterna Sterol Biosynthetic Process Golgi Medial Cisterna Ubiquitin Protein Ligase Binding Regulation Of Protein Ubiquitination Ephrin Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity Positive Regulation Of Stress Fiber Assembly Protein Catabolic Process Endoplasmic Reticulum Regulation Of Protein K63-linked Ubiquitination	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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