GLIPR2 and PNMA5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GLIPR2	PNMA5
Description		GLI pathogenesis related 2	PNMA family member 5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Membrane Extracellular Exosome	Nucleus
	Molecular Function	Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Sexual Reproduction Positive Regulation Of ERK1 And ERK2 Cascade	Positive Regulation Of Apoptotic Process
Pathways
Drugs		L-cysteic acid
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172)
Interacting Genes		3 interacting genes: FBXO7 KRTAP10-3 PNMA5	59 interacting genes: AP1M1 APPL1 ARPC4 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CSTPP1 CTNNA3 DDX6 DRC4 DZIP1L EHHADH FOXH1 FSD2 GLIPR2 GOLGA6L9 GORASP2 GPRASP3 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1
Entrez ID		152007	114824
HPRD ID		06187	06678
Ensembl ID		ENSG00000122694	ENSG00000198883
Uniprot IDs		A0A087WUM5 A0A088AWP7 Q5VZR0 Q9H4G4	Q96PV4
PDB IDs		1SMB 4AIW 5VHG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Lymphocyte Differentiation Autophagy Of Mitochondrion Ligase Inhibitor Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Hemopoiesis Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Lymphocyte Activation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Leukocyte Activation Senescence-associated Heterochromatin Focus Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Lewy Body Core Regulation Of Lymphocyte Differentiation Negative Regulation Of Cell Activation Negative Regulation Of Immature T Cell Proliferation Mitochondrial Depolarization Oncogene-induced Cell Senescence Positive Regulation Of Apoptotic Process Involved In Morphogenesis Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Polyubiquitination Ubiquitin Ligase Inhibitor Activity Autophagy Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Cell Development Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Cell Cycle Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Stability Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator	XPC Complex Cytoskeleton Protein Binding Cytoplasm
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