PLB1 and S100A1

Number of citations of the paper that reports this interaction (PMID 12804600)
12

Data Source:
BioGRID (affinity chromatography technology, pull down)

		PLB1	S100A1
Gene Name		phospholipase B1	S100 calcium binding protein A1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane	Nucleus Sarcoplasmic Reticulum Z Disc M Band Neuron Projection Protein Complex
	Molecular Function	Lysophospholipase Activity Phospholipase A2 Activity	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Retinoid Metabolic Process Phospholipid Metabolic Process Phototransduction, Visible Light Lipid Catabolic Process Phosphatidylcholine Acyl-chain Remodeling Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process Positive Regulation Of Acrosome Reaction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity
Pathways		Metabolism of lipids and lipoproteins Visual phototransduction Phospholipid metabolism Glycerophospholipid biosynthesis Acyl chain remodelling of PC Diseases associated with visual transduction Retinoid metabolism and transport
Drugs			Olopatadine
Diseases
GWAS
Protein-Protein Interactions		1 interactors: S100A1	24 interactors: ACTA1 AGER ANXA6 ATP2A2 CACYBP CAPZA1 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		151056	6271
HPRD ID		15141	01489
Ensembl ID		ENSG00000163803	ENSG00000160678
Uniprot IDs		B2RWP8 Q6P1J6	P23297
PDB IDs			2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cation Channel Activity Substantia Nigra Development Positive Regulation Of Ion Transmembrane Transporter Activity Neural Nucleus Development Positive Regulation Of Transporter Activity Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Midbrain Development Positive Regulation Of Calcium Ion Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Heart Contraction Regulation Of Calcium Ion Transport Positive Regulation Of Ion Transport	Muscle System Process Response To Abiotic Stimulus Regulation Of Cardiac Muscle Cell Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Protein Complex Assembly Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Striated Muscle Contraction Glycogen Catabolic Process Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Polysaccharide Catabolic Process Calcium Ion Transport Relaxation Of Muscle Striated Muscle Tissue Development Negative Regulation Of Heart Contraction Skeletal Muscle Fiber Development Response To Hormone Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Metal Ion Muscle Tissue Development Cellular Component Assembly Myotube Cell Development Regulation Of Cellular Localization Cellular Carbohydrate Catabolic Process Regulation Of The Force Of Heart Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Response To Wounding Regulation Of Ion Homeostasis Regulation Of Actin Filament-based Process Cellular Metal Ion Homeostasis Cellular Response To Alkaloid Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Astrocyte Differentiation Cytosolic Calcium Ion Homeostasis Cellular Cation Homeostasis Actin-mediated Cell Contraction Cellular Ion Homeostasis Response To Peptide Hormone Cardiac Conduction Tissue Development Negative Regulation Of Striated Muscle Tissue Development Steroid Hormone Receptor Complex Assembly Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Positive Regulation Of Schwann Cell Proliferation
Tagcloud ?		buffers chase crz1 curtails deacylation exacerbates glucocorticoid glycerophosphocholine hydrolyzes impacts lacks lcb1 message myriocin pc perturbation phosphatidylcholine phospholipase phospholipid probed pulse radiolabeling resides sgk1 slowed sphingolipid turnover ypk1 ypk1delta	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Difference) ?		buffers chase crz1 curtails deacylation exacerbates glucocorticoid glycerophosphocholine hydrolyzes impacts lacks lcb1 message myriocin pc perturbation phosphatidylcholine phospholipase phospholipid probed pulse radiolabeling resides sgk1 slowed sphingolipid turnover ypk1 ypk1delta	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Intersection) ?