CDPF1 and PHLDA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDPF1	PHLDA1
Description		cysteine rich DPF motif domain containing 1	pleckstrin homology like domain family A member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process		Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways			Interaction between PHLDA1 and AURKA MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Triglyceride levels ( 32154731)	Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Atrial fibrillation ( 29892015 30061737) Blood trace element (Cu levels) ( 23720494) Blood urea nitrogen levels ( 29403010 31152163) Creatinine levels ( 29403010) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Estimated glomerular filtration rate ( 30604766 31152163) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 26831199) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		19 interacting genes: APP BHLHE40 CATSPER1 CREB5 DDIT4L EFEMP2 ENKD1 FAM221A FRS3 HDAC4 HOXA1 KCTD9 LGALS4 MISP PHLDA1 PTGER4 TFAP2D VGLL3 ZIC1	43 interacting genes: APP CDPF1 CREBBP CYSRT1 EIF3D F2RL1 FBXO7 HSPA4 HSPA4L KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP5-1 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS13 MDFI NBPF19 NOTCH2NLA PABPC4 PLSCR1 RPL14 TRAF4 TRAF6 TRIM42 TSPAN4
Entrez ID		150383	22822
HPRD ID		11241	05625
Ensembl ID		ENSG00000205643	ENSG00000139289
Uniprot IDs		F6UL18 Q6NVV7	Q8WV24
PDB IDs
Enriched GO Terms of Interacting Partners?			Intermediate Filament Keratin Filament Cytosol Regulation Of JNK Cascade Positive Regulation Of JNK Cascade
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