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CTNNB1 and TGFBR1
Number of citations of the paper that reports this interaction (PubMedID
12000714
)
33
Data Source:
HPRD
(in vivo)
CTNNB1
TGFBR1
Description
catenin beta 1
transforming growth factor beta receptor 1
Image
GO Annotations
Cellular Component
Euchromatin
Spindle Pole
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Adherens Junction
Fascia Adherens
Bicellular Tight Junction
Focal Adhesion
Cilium
Cell Cortex
Intercalated Disc
Membrane
Basolateral Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Catenin Complex
Flotillin Complex
Z Disc
Lamellipodium
Cell Junction
Beta-catenin Destruction Complex
Cell Projection Membrane
Microvillus Membrane
Protein-containing Complex
Protein-DNA Complex
Scrib-APC-beta-catenin Complex
Ciliary Basal Body
Presynaptic Membrane
Cell Projection
Apical Junction Complex
Apical Part Of Cell
Synapse
Postsynaptic Membrane
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Anchoring Junction
Beta-catenin-TCF7L2 Complex
Catenin-TCF7L2 Complex
Cell Periphery
RNA Polymerase II Transcription Regulator Complex
Schaffer Collateral - CA1 Synapse
Presynaptic Active Zone Cytoplasmic Component
Glutamatergic Synapse
Postsynaptic Density, Intracellular Component
Beta-catenin-ICAT Complex
Beta-catenin-TCF Complex
Wnt Signalosome
Nucleus
Nucleoplasm
Endosome
Plasma Membrane
Bicellular Tight Junction
Cilium
Cell Surface
Membrane
Receptor Complex
Membrane Raft
Activin Receptor Complex
Transforming Growth Factor Beta Ligand-receptor Complex
Anchoring Junction
Serine/threonine Protein Kinase Complex
Molecular Function
Transcription Coregulator Binding
Transcription Corepressor Binding
Chromatin Binding
Transcription Coactivator Activity
Signaling Receptor Binding
Protein Binding
Nuclear Receptor Binding
Enzyme Binding
Kinase Binding
Protein Kinase Binding
Phosphatase Binding
Protein Phosphatase Binding
Nuclear Estrogen Receptor Binding
Ubiquitin Protein Ligase Binding
Transmembrane Transporter Binding
Alpha-catenin Binding
Cadherin Binding
SMAD Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
I-SMAD Binding
Disordered Domain Specific Binding
DNA-binding Transcription Factor Binding
Histone Methyltransferase Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity
Transforming Growth Factor Beta Receptor Activity, Type I
Signaling Receptor Binding
Type II Transforming Growth Factor Beta Receptor Binding
Protein Binding
ATP Binding
Kinase Activity
Activin Receptor Activity, Type I
Transferase Activity
Growth Factor Binding
Ubiquitin Protein Ligase Binding
SMAD Binding
Metal Ion Binding
Activin Binding
Transforming Growth Factor Beta Binding
I-SMAD Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
Protein Polyubiquitination
Embryonic Axis Specification
Cell Morphogenesis
Skeletal System Development
Branching Involved In Blood Vessel Morphogenesis
Vasculogenesis
Osteoblast Differentiation
Branching Involved In Ureteric Bud Morphogenesis
In Utero Embryonic Development
Gastrulation With Mouth Forming Second
Endoderm Formation
Cell Fate Specification
Endodermal Cell Fate Commitment
Neuron Migration
Kidney Development
Epithelial To Mesenchymal Transition
Neural Plate Development
Tissue Homeostasis
Vasculature Development
Positive Regulation Of Neuroblast Proliferation
Positive Regulation Of Mesenchymal Cell Proliferation
Chondrocyte Differentiation
Lens Morphogenesis In Camera-type Eye
Outflow Tract Morphogenesis
Regulation Of Secondary Heart Field Cardioblast Proliferation
Metanephros Morphogenesis
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Cell Adhesion
Cell-matrix Adhesion
Epidermal Growth Factor Receptor Signaling Pathway
Chemical Synaptic Transmission
Ectoderm Development
Nervous System Development
Glial Cell Fate Determination
Neuroblast Proliferation
Heart Development
Intracellular Protein Localization
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Xenobiotic Stimulus
Anterior/posterior Axis Specification
Dorsal/ventral Axis Specification
Dorsal/ventral Pattern Formation
Proximal/distal Pattern Formation
Mesenchymal Cell Proliferation
Gene Expression
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Wnt Signaling Pathway
Morphogenesis Of Embryonic Epithelium
Negative Regulation Of Angiogenesis
Stem Cell Population Maintenance
Layer Formation In Cerebral Cortex
Hypothalamus Development
Central Nervous System Vasculogenesis
Hair Cycle Process
Hemopoiesis
Cell Differentiation
Neuron Differentiation
T Cell Differentiation
Osteoclast Differentiation
Lung Development
Male Genitalia Development
Epithelial Cell Differentiation
Regulation Of Epithelial Cell Differentiation
Positive Regulation Of Epithelial Cell Differentiation
Forebrain Development
Midbrain Development
Hindbrain Development
Regulation Of Centriole-centriole Cohesion
Pancreas Development
Hair Follicle Morphogenesis
Regulation Of Protein Ubiquitination
Regulation Of Myelination
Positive Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Chondrocyte Differentiation
Response To Estradiol
Positive Regulation Of Transcription Elongation By RNA Polymerase II
T Cell Differentiation In Thymus
Negative Regulation Of Protein Sumoylation
Positive Regulation Of Homotypic Cell-cell Adhesion
Adherens Junction Organization
Adherens Junction Assembly
Protein Localization To Cell Surface
Embryonic Heart Tube Development
Genitalia Morphogenesis
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Hair Cell Differentiation
Detection Of Muscle Stretch
Embryonic Skeletal Limb Joint Morphogenesis
Astrocyte-dopaminergic Neuron Signaling
Regulation Of Cell Population Proliferation
Regulation Of T Cell Proliferation
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of MAPK Cascade
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Neuron Apoptotic Process
Skin Development
Cell-cell Adhesion Mediated By Cadherin
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Bone Resorption
Regulation Of Cell Differentiation
Negative Regulation Of Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Endothelial Cell Differentiation
Regulation Of Osteoblast Differentiation
Positive Regulation Of Osteoblast Differentiation
Regulation Of Osteoclast Differentiation
Negative Regulation Of Osteoclast Differentiation
Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Angiogenesis
Positive Regulation Of Angiogenesis
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Regulation Of Fibroblast Proliferation
Cell Maturation
Synaptic Vesicle Transport
Animal Organ Development
Thymus Development
Embryonic Organ Development
Oocyte Development
Embryonic Foregut Morphogenesis
Positive Regulation Of Skeletal Muscle Tissue Development
Regulation Of Smooth Muscle Cell Proliferation
Neuron Fate Determination
Oligodendrocyte Differentiation
Negative Regulation Of Oligodendrocyte Differentiation
Regulation Of Neurogenesis
Negative Regulation Of Neurogenesis
Synapse Organization
Detection Of Mechanical Stimulus
Smooth Muscle Cell Differentiation
Myoblast Proliferation
Regulation Of Timing Of Anagen
Regulation Of Synapse Assembly
Oviduct Development
Canonical Wnt Signaling Pathway
Limb Development
Mesenchymal To Epithelial Transition
Trachea Morphogenesis
Trachea Formation
Epithelial Tube Branching Involved In Lung Morphogenesis
Lung Cell Differentiation
Lung-associated Mesenchyme Development
Lung Epithelial Cell Differentiation
Lung Induction
Epithelial Cell Differentiation Involved In Prostate Gland Development
Epithelial Cell Proliferation Involved In Prostate Gland Development
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Hair Follicle Placode Formation
Establishment Of Blood-brain Barrier
Mesenchymal Cell Proliferation Involved In Lung Development
Positive Regulation Of Branching Involved In Lung Morphogenesis
Endothelial Tube Morphogenesis
Fungiform Papilla Formation
Sympathetic Ganglion Development
Cranial Ganglion Development
Regulation Of Centromeric Sister Chromatid Cohesion
Cellular Response To Growth Factor Stimulus
Cellular Response To Indole-3-methanol
Renal Vesicle Formation
Renal Inner Medulla Development
Renal Outer Medulla Development
Nephron Tubule Formation
Stem Cell Proliferation
Regulation Of Nephron Tubule Epithelial Cell Differentiation
Mesenchymal Stem Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Calcium Ion Import
Acinar Cell Differentiation
Synaptic Vesicle Clustering
Apoptotic Signaling Pathway
Cell-cell Adhesion
Positive Regulation Of Odontoblast Differentiation
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cranial Skeletal System Development
Midbrain Dopaminergic Neuron Differentiation
Positive Regulation Of Blood Vessel Branching
Neuron Projection Extension
Embryonic Brain Development
Dorsal Root Ganglion Development
Establishment Of Blood-retinal Barrier
Regulation Of Protein Localization To Cell Surface
Positive Regulation Of Determination Of Dorsal Identity
Positive Regulation Of Neural Precursor Cell Proliferation
Positive Regulation Of Myoblast Proliferation
Positive Regulation Of Stem Cell Proliferation
Negative Regulation Of Apoptotic Signaling Pathway
Skeletal System Development
Angiogenesis
In Utero Embryonic Development
Kidney Development
Blastocyst Development
Epithelial To Mesenchymal Transition
Endothelial Cell Proliferation
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Endothelial Cell Proliferation
Lens Development In Camera-type Eye
Ventricular Trabecula Myocardium Morphogenesis
Ventricular Compact Myocardium Morphogenesis
Proepicardium Development
Regulation Of DNA-templated Transcription
Apoptotic Process
Signal Transduction
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Nervous System Development
Heart Development
Positive Regulation Of Cell Population Proliferation
Germ Cell Migration
Male Gonad Development
Post-embryonic Development
Anterior/posterior Pattern Specification
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Epithelial To Mesenchymal Transition
Peptidyl-serine Phosphorylation
Cell Differentiation
Collagen Fibril Organization
Positive Regulation Of Cell Growth
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Regulation Of Protein Ubiquitination
Negative Regulation Of Chondrocyte Differentiation
Activin Receptor Signaling Pathway
Intracellular Signal Transduction
Myofibroblast Differentiation
Wound Healing
Endothelial Cell Activation
Extracellular Structure Organization
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Endothelial Cell Migration
Positive Regulation Of DNA-templated Transcription
Filopodium Assembly
Thymus Development
Neuron Fate Commitment
Embryonic Cranial Skeleton Morphogenesis
Skeletal System Morphogenesis
Mesenchymal Cell Differentiation
Artery Morphogenesis
Cell Motility
Positive Regulation Of Filopodium Assembly
Positive Regulation Of Stress Fiber Assembly
Regulation Of Cell Cycle
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Parathyroid Gland Development
Roof Of Mouth Development
Pharyngeal System Development
Regulation Of Cardiac Muscle Cell Proliferation
Cardiac Epithelial To Mesenchymal Transition
Positive Regulation Of SMAD Protein Signal Transduction
Ventricular Septum Morphogenesis
Angiogenesis Involved In Coronary Vascular Morphogenesis
Coronary Artery Morphogenesis
Trophoblast Cell Migration
Response To Cholesterol
Cellular Response To Growth Factor Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Alcohol
Vascular Endothelial Cell Proliferation
Positive Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Mesenchymal Stem Cell Proliferation
Positive Regulation Of Vasculature Development
Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Positive Regulation Of Tight Junction Disassembly
Epicardium Morphogenesis
Regulation Of Multicellular Organismal Development
Positive Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
TCF dependent signaling in response to WNT
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Apoptotic cleavage of cell adhesion proteins
Deactivation of the beta-catenin transactivating complex
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Ca2+ pathway
Adherens junctions interactions
Binding of TCF/LEF:CTNNB1 to target gene promoters
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
VEGFR2 mediated vascular permeability
Myogenesis
Myogenesis
Signaling by GSK3beta mutants
CTNNB1 S33 mutants aren't phosphorylated
CTNNB1 S37 mutants aren't phosphorylated
CTNNB1 S45 mutants aren't phosphorylated
CTNNB1 T41 mutants aren't phosphorylated
RHO GTPases activate IQGAPs
Transcriptional Regulation by VENTX
InlA-mediated entry of Listeria monocytogenes into host cells
RUNX3 regulates WNT signaling
Cardiogenesis
Germ layer formation at gastrulation
Regulation of CDH11 function
Regulation of CDH11 function
Regulation of CDH19 Expression and Function
Regulation of CDH1 Function
Degradation of CDH1
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Formation of paraxial mesoderm
Formation of axial mesoderm
Formation of definitive endoderm
Somitogenesis
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Formation of the nephric duct
CDH11 homotypic and heterotypic interactions
Specification of the neural plate border
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Transcriptional and post-translational regulation of MITF-M expression and activity
Regulation of PD-L1(CD274) transcription
Downregulation of TGF-beta receptor signaling
Downregulation of TGF-beta receptor signaling
TGF-beta receptor signaling activates SMADs
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
SMAD2/3 Phosphorylation Motif Mutants in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
TGFBR1 KD Mutants in Cancer
TGFBR1 LBD Mutants in Cancer
UCH proteinases
Ub-specific processing proteases
TGFBR3 regulates TGF-beta signaling
Drugs
Urea
4-(3-Pyridin-2-Yl-1h-Pyrazol-4-Yl)Quinoline
Naphthyridine Inhibitor
3-(4-Fluorophenyl)-2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4h-Pyrrolo[1,2-B]Pyrazole
N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide
2-(6-methylpyridin-2-yl)-N-pyridin-4-ylquinazolin-4-amine
N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine
Fostamatinib
Diseases
Pilomatricoma; Epithelioma calcificans of Malherbe
Gastric cancer
Hepatocellular carcinoma
Thyroid cancer
Colorectal cancer
Endometrial Cancer
Loeys-Dietz syndrome (LDS)
Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS
Bone mineral density (hip) (
19801982
27311723
)
Bone mineral density (total hip) (
29883787
)
Colorectal cancer (
26151821
)
Colorectal cancer or advanced adenoma (
30510241
)
Femoral neck bone mineral density (
22504420
29499414
)
Fractures (
30158200
)
Heel bone mineral density (
28869591
30598549
)
High myopia (
31816047
)
Lumbar spine bone mineral density (
29499414
)
Refractive error (
32231278
)
Systolic blood pressure (
30224653
)
Advanced age-related macular degeneration (
26691988
)
Age-related macular degeneration (
23455636
)
Asthma (
31959851
32296059
34103634
)
Callous-unemotional behaviour (
23874384
)
Cough in response to angiotensin-converting enzyme inhibitor drugs (
28084903
)
Dental caries (
23064961
)
Epithelial ovarian cancer (
25134534
)
Fractures (paediatric) (
32742401
)
Gestational age at birth (maternal effect) (
28877031
)
Refractive error (
32231278
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
205 interacting genes:
ACP1
AJAP1
AKT1
AMER1
APC
APC2
APP
AR
ARFGEF1
ARHGAP32
ASH2L
AXIN1
AXIN2
BCL3
BCL6
BCL9
BCL9L
BOC
BRCA1
BTRC
CA9
CARM1
CASP3
CASP8
CBL
CBY1
CCAR1
CCDC88A
CCND1
CDC27
CDC73
CDH1
CDH11
CDH15
CDH16
CDH2
CDH24
CDH3
CDH5
CDH7
CDH8
CDH9
CDK1
CDK2
CDK5R1
CDK6
CDON
CEBPA
CHD8
CHUK
CREBBP
CSNK1A1
CSNK1D
CSNK2A1
CSNK2B
CTNNA1
CTNNA3
CTNNBIP1
CTNND2
DLG5
DSC3
DVL1
DVL3
EGFR
ELAVL1
EP300
ERBB2
ERBIN
ESM1
ESR1
EZR
FBXW2
FER
FERMT2
FHIT
FHL2
FLT1
FLT3
FOXO1
FOXO4
FSCN1
FUS
FYN
GLIS2
GNA13
GRIK2
GRIN1
GRIN2D
GSK3B
H1-2
HIF1A
HNF1A
HNF4A
IGF2BP1
IKBKB
IQGAP1
JADE1
KAT2A
KAT2B
KDR
KMT2A
KMT2D
LATS2
LEF1
LEO1
MAGI1
MAGI2
MAP3K2
MAPK8
MAPK9
MEG3
MEN1
MET
MITF
MUC1
NAA10
NCOA2
NDRG1
NEK2
NEURL2
NF2
NFKB1
NHERF1
NOTCH1
NR5A1
NR5A2
PECAM1
PFKFB3
PICK1
PIK3R1
PIN1
PITX2
PKD1
PKM
PKP2
PLK1
PPM1A
PRKCG
PSEN1
PSEN2
PTGS2
PTPN1
PTPN13
PTPN14
PTPN6
PTPRF
PTPRJ
PTPRK
PTPRM
PTPRU
PTPRZ1
PYGO1
RAPGEF2
RBBP5
RIPK1
RUVBL1
RUVBL2
RXRA
SALL1
SEC62
SHCBP1
SLC30A9
SMAD2
SMAD3
SMAD4
SMAD7
SMARCA4
SMARCA5
SMURF1
SOX1
SOX10
SOX17
SP1
SPN
SRC
STUB1
SYNE2
TAX1BP3
TBL1X
TCF3
TCF4
TCF7L1
TCF7L2
TFAP2A
TGFBR1
TGFBR2
TLE1
TRIM26
TRIM33
TRIM55
TRIM63
TRIP10
TRRAP
TSC1
UBC
UBE2B
UBE2D1
UBE2R2
UBE3A
UHRF2
USP10
USP13
USP9X
ZFYVE9
ZIC3
164 interacting genes:
ACVR1
ACVRL1
AMHR2
ANAPC5
AP2B1
ARHGAP15
ARHGAP31
ARHGEF6
ARL4D
ARL8B
ASH2L
AURKB
BAMBI
BMPR1B
BMPR2
BTBD2
CAV1
CD44
CDC20
CDC42EP4
CDK14
CDK17
CDK4
CDK6
CDKL1
CHN1
CHN2
CHUK
CLU
CSNK1A1
CSNK2A2
CTNNB1
CUL5
DAB2
DAPK2
DCAF12
DCAF6
DUSP13B
EIF2AK4
ENC1
ENG
FANCL
FBXL12
FBXO34
FKBP1A
FKBP1B
FNTA
GNA13
GNB2
GNB3
IKBKB
ITK
KATNB1
KCNK18
KLHL1
KLHL35
LIMS1
LITATS1
MAP3K20
MAP3K7
MYO3A
MYOC
MYT1L
NAT8
NEK6
NEK8
NKIRAS1
NRP1
NUAK2
NUP37
OSR1
OTUB1
OXSR1
PAK1
PARD6A
PIK3R1
PIK3R2
PLEK
PLEKHB1
PLEKHJ1
PLK4
PML
POMK
PPP2R2A
PPP3CC
PPP6C
PREB
PREX2
PRPF4
RAB13
RAB25
RAB33B
RAB34
RAB38
RAB3B
RAB6B
RAN
RAP2A
RASD2
RASL12
RGS19
RHEBL1
RHOA
RHOD
RHOG
RHOH
RHOJ
RHPN2
RNF130
RNF146
RNF5
RPAP3
RPS27A
RRH
RTKN
SAMD8
SAT2
SKAP2
SKI
SKIC8
SMAD1
SMAD2
SMAD3
SMAD4
SMAD6
SMAD7
SMURF2
SNTG1
SNX6
SOCS6
SQSTM1
STK35
STRAP
STUB1
STX8
STYXL1
TGFB1
TGFB2
TGFB3
TGFBR2
TGFBRAP1
TNNT1
TRAF6
TRAP1
TSC22D1
TSSK1B
TSSK4
TTC1
TTC27
TTPAL
UBA52
UBB
UBD
UBE2E3
UBE2Z
UBXN1
USP14
USP2
USP45
VEPH1
WDR13
WDR33
XIAP
ZFYVE9
Entrez ID
1499
7046
HPRD ID
00286
01822
Ensembl ID
ENSG00000168036
ENSG00000106799
Uniprot IDs
B4DGU4
P35222
B4DXN7
B4DY26
F8W0K6
P36897
Q5T7S2
PDB IDs
1G3J
1JDH
1JPW
1LUJ
1P22
1QZ7
1T08
1TH1
2G57
2GL7
2Z6H
3DIW
3FQN
3FQR
3SL9
3SLA
3TX7
4DJS
6M90
6M91
6M92
6M93
6M94
6O9B
6O9C
6WLX
6WNX
7AFW
7AR4
7UWI
7UWO
7ZRB
8EI9
8EIA
8EIB
8EIC
8RU3
8RU4
8VME
8VMF
8Y0G
8Y0P
8Y14
8Z0U
8Z10
8Z5J
8Z61
1B6C
1IAS
1PY5
1RW8
1VJY
2L5S
2PJY
2WOT
2WOU
2X7O
3FAA
3GXL
3HMM
3KCF
3KFD
3TZM
4X0M
4X2F
4X2G
4X2J
4X2K
4X2N
5E8S
5E8T
5E8U
5E8W
5E8X
5E8Z
5E90
5FRI
5QIK
5QIL
5QIM
5QTZ
5QU0
5USQ
6B8Y
6MAC
8YHF
8YHL
9B9F
9F6X
9FK5
Enriched GO Terms of Interacting Partners
?
Beta-catenin Binding
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Signal Transduction
Regulation Of Wnt Signaling Pathway
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Developmental Process
Positive Regulation Of Signal Transduction
Regulation Of Primary Metabolic Process
Positive Regulation Of Signaling
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Developmental Process
Regulation Of Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Programmed Cell Death
Cellular Developmental Process
Regulation Of Multicellular Organismal Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Apoptotic Process
Negative Regulation Of Macromolecule Metabolic Process
Anatomical Structure Morphogenesis
Nucleoplasm
Nucleus
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Regulation Of Intracellular Signal Transduction
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Signal Transduction
Intracellular Signaling Cassette
Signal Transduction
Protein Serine/threonine Kinase Activity
Nucleotide Binding
Protein Kinase Activity
Regulation Of Signaling
Regulation Of Cell Communication
Type I Transforming Growth Factor Beta Receptor Binding
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Intracellular Signal Transduction
Regulation Of SMAD Protein Signal Transduction
SMAD Binding
Cytosol
Kinase Activity
Response To Growth Factor
GTPase Activity
Cell Surface Receptor Signaling Pathway
Protein Modification Process
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of SMAD Protein Signal Transduction
Ubiquitin Protein Ligase Binding
Negative Regulation Of Signal Transduction
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Protein Serine Kinase Activity
Positive Regulation Of Epithelial To Mesenchymal Transition
I-SMAD Binding
Modification-dependent Protein Catabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Proteolysis Involved In Protein Catabolic Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Epithelial To Mesenchymal Transition
GTP Binding
Regulation Of Cellular Response To Growth Factor Stimulus
Heteromeric SMAD Protein Complex
Transferase Activity
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Binding
SMAD Protein Signal Transduction
Post-translational Protein Modification
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