CTH and SDCBP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CTH	SDCBP2
Gene Name		cystathionine gamma-lyase	syndecan binding protein (syntenin) 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Cystathionine Gamma-lyase Activity Protein Binding Calmodulin Binding Carbon-sulfur Lyase Activity Pyridoxal Phosphate Binding L-cystine L-cysteine-lyase (deaminating) Homocysteine Desulfhydrase Activity L-cysteine Desulfhydrase Activity	Protein C-terminus Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Sulfur Amino Acid Catabolic Process Cysteine Metabolic Process Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Cysteine Biosynthetic Process Transsulfuration Endoplasmic Reticulum Unfolded Protein Response Cellular Nitrogen Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Small Molecule Metabolic Process Protein Sulfhydration Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Homotetramerization Hydrogen Sulfide Biosynthetic Process Negative Regulation Of Apoptotic Signaling Pathway	Nervous System Development Intracellular Signal Transduction Intracellular Transport
Pathways		Degradation of cysteine and homocysteine Sulfur amino acid metabolism Cysteine formation from homocysteine Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate L-Cysteine 2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol L-2-amino-3-butynoic acid
Diseases
GWAS
Protein-Protein Interactions		4 interactors: GUCD1 RECK SDCBP2 WDYHV1	41 interactors: ADAP1 ARF4 BEND7 C11orf57 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR NFASC NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		1491	27111
HPRD ID		09633	18032
Ensembl ID		ENSG00000116761	ENSG00000125775
Uniprot IDs		P32929	Q9H190
PDB IDs		2NMP 3COG 3ELP
Enriched GO Terms of Interacting Partners?			RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Cellular Component Assembly Protein Complex Assembly Involved In Synapse Maturation Fertilization, Exchange Of Chromosomal Proteins Gamma-aminobutyric Acid Receptor Clustering Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Cellular Nitrogen Compound Metabolic Process Locomotion MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Assembly Male Pronucleus Assembly Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Protein-pyridoxal-5-phosphate Linkage Transsulfuration Tryptophan Catabolic Process To Acetyl-CoA Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Gephyrin Clustering Synaptic Vesicle Clustering Hydrogen Sulfide Biosynthetic Process
Tagcloud ?		additionally allows cbs contribution cystathionase cystathionine cysteine determination employed evaluating gamma glutathione gsh gssg h2s homogenates homoserine hplc inhibiting ketobutyrate measure propargylglycine reactions redox reflect rp synthase totally undertaken
Tagcloud (Difference) ?		additionally allows cbs contribution cystathionase cystathionine cysteine determination employed evaluating gamma glutathione gsh gssg h2s homogenates homoserine hplc inhibiting ketobutyrate measure propargylglycine reactions redox reflect rp synthase totally undertaken
Tagcloud (Intersection) ?