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ZNRF4 and UBE2G2
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
ZNRF4
UBE2G2
Gene Name
zinc and ring finger 4
ubiquitin-conjugating enzyme E2G 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Integral Component Of Membrane
Endoplasmic Reticulum
Cytosol
Molecular Function
Zinc Ion Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein N-linked Glycosylation Via Asparagine
ER-associated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2G2
UBE2N
UBE2W
37 interactors:
AMFR
ARL14
BIRC8
CBL
CNNM3
CPOX
CUL9
FARP2
HBS1L
HERPUD1
KDM2A
KIAA0368
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
PARK2
POLR3F
RBX1
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
Entrez ID
148066
7327
HPRD ID
15895
04387
Ensembl ID
ENSG00000105428
ENSG00000184787
Uniprot IDs
Q8WWF5
P60604
PDB IDs
2CYX
2KLY
2LXP
3H8K
4LAD
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Modification Process
Proteasomal Protein Catabolic Process
Toll-like Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Proteolysis
Activation Of Innate Immune Response
Protein K63-linked Ubiquitination
Cellular Protein Metabolic Process
Protein Monoubiquitination
Positive Regulation Of Innate Immune Response
Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Regulation Of Innate Immune Response
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Protein Metabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Response To Oxygen Levels
Positive Regulation Of Protein Ubiquitination
Immune Response-regulating Signaling Pathway
Regulation Of Protein Ubiquitination
Regulation Of Chromosome Organization
Positive Regulation Of Immune Response
Mitotic Spindle Assembly Checkpoint
Histone Ubiquitination
Spindle Assembly Checkpoint
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Cellular Response To Stress
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Catabolic Process
Proteolysis
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
ER-associated Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Cellular Response To Stress
Cellular Metabolic Process
Regulation Of Proteolysis
Regulation Of Signaling
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Signal Transduction
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Protein Ubiquitination
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Signal Transduction
Protein K63-linked Ubiquitination
Cellular Response To Topologically Incorrect Protein
Negative Regulation Of Mitochondrial Fusion
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signaling
Regulation Of Mitochondrial Fusion
Protein Autoubiquitination
Response To Stimulus
Response To Unfolded Protein
Regulation Of Protein Stability
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Cellular Protein Catabolic Process
Cellular Response To Stimulus
Response To Organic Substance
Positive Regulation Of Mitochondrial Fission
Regulation Of Intracellular Signal Transduction
Response To Stress
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud
?
alters
assembly
attack
bond
catalyzes
chain
chains
cooperative
cooperatively
correct
cue
distal
donor
drive
e3
elusive
g2br
gp78
helps
lys48
monoubiquitin
orientation
polyubiquitin
preassembled
preferential
thioester
transferring
ubiquitin
Tagcloud (Difference)
?
alters
assembly
attack
bond
catalyzes
chain
chains
cooperative
cooperatively
correct
cue
distal
donor
drive
e3
elusive
g2br
gp78
helps
lys48
monoubiquitin
orientation
polyubiquitin
preassembled
preferential
thioester
transferring
ubiquitin
Tagcloud (Intersection)
?