CSTF3 and CPSF1

Number of citations of the paper that reports this interaction (PMID 7590244)
87

Data Source:
BioGRID (pull down)

		CSTF3	CPSF1
Gene Name		cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa	cleavage and polyadenylation specific factor 1, 160kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	RNA Binding MRNA Binding Poly(A) RNA Binding	MRNA 3'-UTR Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA Splicing Gene Expression MRNA 3'-end Processing	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing Processing of Intronless Pre-mRNAs	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Transport of Mature mRNA Derived from an Intronless Transcript RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Cleavage of Growing Transcript in the Termination Region mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Intronless Pre-mRNAs Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CPSF1 CSTF1 CSTF2 RRAGA	18 interactors: CSTF2T CSTF3 CTD GLIS2 HMOX1 IL7R MCM2 NEDD4 PAPOLA POLR2A PRRC2A REL RRAGA TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		1479	29894
HPRD ID		02651	05823
Ensembl ID		ENSG00000176102	ENSG00000071894
Uniprot IDs		Q12996	Q10570
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Cleavage MRNA Polyadenylation RNA Polyadenylation Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleic Acid Phosphodiester Bond Hydrolysis RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytolysis Transcription, DNA-templated Positive Regulation Of TOR Signaling Modulation By Virus Of Host Morphology Or Physiology RNA Biosynthetic Process RNA Metabolic Process Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus Gene Expression MRNA Export From Nucleus RNA Export From Nucleus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Interaction With Host Regulation Of Autophagy	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Processing RNA Polyadenylation Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Termination Of RNA Polymerase II Transcription MRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Spermine Transport Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Viral Transcription Response To Cytokine Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Viral Process
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