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CSTF3
Description
cleavage stimulation factor subunit 3
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
MRNA Cleavage Stimulating Factor Complex
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Biological Process
RNA Processing
MRNA Processing
RNA 3'-end Processing
MRNA 3'-end Processing
Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Pathways
mRNA 3'-end processing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Anger (
24489884
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Novel Interacting Genes
3 novel interacting genes:
CD44
DNAH7
PAX6
Interacting Genes
15 interacting genes:
CEBPA
CSTF1
CSTF2
DLGAP1-AS2
MIR128-2
MIR138-2
MIR15B
MIR19A
MIR19B1
MIR21
MIR92A2
MIRLET7A3
MIRLET7F2
MIRLET7G
MIRLET7I
Entrez ID
1479
HPRD ID
02651
Ensembl ID
ENSG00000176102
Uniprot IDs
Q12996
PDB IDs
6B3X
6URO
7ZY4
Enriched GO Terms of Interacting Partners
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RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Extracellular Vesicle
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Regulation Of Inflammatory Response
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition
Positive Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Negative Regulation Of Defense Response
MRNA 3'-UTR Binding
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Matrix Metallopeptidase Secretion
Negative Regulation Of Cell Migration
Regulation Of Muscle Cell Differentiation
Regulation Of Cardiac Muscle Cell Apoptotic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cell Motility
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Muscle Cell Apoptotic Process
Negative Regulation Of Locomotion
Negative Regulation Of Inflammatory Response
Negative Regulation Of Translation
Negative Regulation Of Cell Differentiation
Regulation Of Extracellular Matrix Organization
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Endothelial Cell Migration
Regulation Of Matrix Metallopeptidase Secretion
Cellular Response To Bacterial Lipopeptide
Regulation Of Cardiac Muscle Hypertrophy
HMG Box Domain Binding
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Response To Bacterial Lipoprotein
Negative Regulation Of Fibroblast Migration
Positive Regulation Of Muscle Cell Differentiation
Regulation Of Defense Response
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