CSTF3 and MIR128-2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		CSTF3	MIR128-2
Description		cleavage stimulation factor subunit 3	microRNA 128-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage Stimulating Factor Complex	RISC Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding
	Biological Process	RNA Processing MRNA Processing RNA 3'-end Processing MRNA 3'-end Processing Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Pathways		mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)	Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary sodium excretion ( 31409800)
Interacting Genes		15 interacting genes: CEBPA CSTF1 CSTF2 DLGAP1-AS2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I	98 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF1 CPSF6 CPSF7 CSTF3 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		1479	406916
HPRD ID		02651
Ensembl ID		ENSG00000176102	ENSG00000207625
Uniprot IDs		Q12996
PDB IDs		6B3X 6URO 7ZY4
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Inflammatory Response Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Defense Response MRNA 3'-UTR Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cell Migration Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Locomotion Negative Regulation Of Inflammatory Response Negative Regulation Of Translation Negative Regulation Of Cell Differentiation Regulation Of Extracellular Matrix Organization Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Endothelial Cell Migration Regulation Of Matrix Metallopeptidase Secretion Cellular Response To Bacterial Lipopeptide Regulation Of Cardiac Muscle Hypertrophy HMG Box Domain Binding Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Positive Regulation Of Muscle Cell Differentiation Regulation Of Defense Response	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Nucleoplasm Ribonucleoprotein Complex Cytoplasmic Stress Granule Regulation Of Translation Spliceosomal Complex Catalytic Step 2 Spliceosome MiRNA Binding MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability Ligase Activity MRNA Stabilization Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process TRNA Metabolic Process Paraspeckles Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway CRD-mediated MRNA Stabilization
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