RAD9B and RAD1

Number of citations of the paper that reports this interaction (PMID 14611806)
5

Data Source:
HPRD (in vivo)

		RAD9B	RAD1
Gene Name		RAD9 homolog B (S. pombe)	RAD1 checkpoint DNA exonuclease
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Checkpoint Clamp Complex	Nucleus Nucleoplasm Chromosome Checkpoint Clamp Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Damaged DNA Binding Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	DNA Damage Checkpoint DNA Catabolic Process, Exonucleolytic DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Substantia Nigra Development Meiotic Recombination Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints	G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: HUS1 HUS1B RAD1 RAD17 RAD9A	15 interactors: COPS5 DNAJC7 FEN1 HUS1 HUS1B MAP1LC3B MSH2 MSH3 MSH6 PARK2 POLB RAD17 RAD9B RPA1 RPA2
Entrez ID		144715	5810
HPRD ID		12221	04400
Ensembl ID		ENSG00000151164	ENSG00000113456
Uniprot IDs		B4DYM6 J3KPN7 Q6WBX8	O60671
PDB IDs			3A1J 3G65 3GGR
Enriched GO Terms of Interacting Partners?		DNA Damage Checkpoint Cell Cycle Checkpoint DNA Repair Cellular Response To DNA Damage Stimulus DNA Replication Cellular Response To Ionizing Radiation Cell Cycle Process DNA Metabolic Process Cell Cycle Negative Regulation Of Cell Cycle Cellular Response To Stress DNA Replication Checkpoint Cellular Response To Radiation Response To Ionizing Radiation Mitotic Cell Cycle Checkpoint Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle DNA Catabolic Process, Exonucleolytic Negative Regulation Of DNA Replication Regulation Of Mitotic Cell Cycle Response To Radiation Response To Stress Negative Regulation Of DNA Metabolic Process Mitotic Cell Cycle Process Regulation Of DNA Replication Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle DNA Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Recombination Checkpoint Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Nucleic Acid Phosphodiester Bond Hydrolysis Cellular Response To Stimulus Intra-S DNA Damage Checkpoint Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Aromatic Compound Catabolic Process Negative Regulation Of Meiotic Nuclear Division Response To Stimulus Negative Regulation Of Meiotic Cell Cycle Biosynthetic Process Substantia Nigra Development Regulation Of Meiosis Regulation Of Meiotic Cell Cycle Neural Nucleus Development Cellular Macromolecule Catabolic Process	DNA Repair Cellular Response To Stress Cellular Response To DNA Damage Stimulus DNA Metabolic Process DNA Recombination Cell Cycle Process Mismatch Repair DNA Replication Meiotic Mismatch Repair DNA Damage Checkpoint Cell Cycle Response To Stress Negative Regulation Of DNA Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Helicase Activity Double-strand Break Repair Nucleobase-containing Compound Metabolic Process Base-excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of DNA Recombination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of DNA Recombination Telomere Maintenance Via Semi-conservative Replication Nitrogen Compound Metabolic Process Nuclear DNA Replication Telomere Maintenance Via Recombination DNA-dependent DNA Replication Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Somatic Recombination Of Immunoglobulin Gene Segments Response To UV Somatic Diversification Of Immunoglobulins Maintenance Of DNA Repeat Elements Mitotic Cell Cycle Checkpoint Meiotic Nuclear Division Cellular Metabolic Process DNA Recombinase Assembly Cellular Response To Stimulus Mitotic Cell Cycle Immunoglobulin Production Meiotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Recombinational Repair Somatic Hypermutation Of Immunoglobulin Genes Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tagcloud ?		1x 3b aminobutyric anxa atg3 autophagy checkpoint enos fenofibrate gabarap homologue huvec lc3b mating metallothionein microtubule mt1x physiologically phytoalexin polyphenolic repeated resveratrol scavenger silent sirt1 umbilical vein wine	abrogates atr bona checkpoint chk1 clamp claspin damaging extensively fide heterotetrameric hus1 impacting irradiation lac laco lacr lastly localizes onto orphan portion rad9 repeats repressor rhino tethering topbp1 uv
Tagcloud (Difference) ?		1x 3b aminobutyric anxa atg3 autophagy enos fenofibrate gabarap homologue huvec lc3b mating metallothionein microtubule mt1x physiologically phytoalexin polyphenolic repeated resveratrol scavenger silent sirt1 umbilical vein wine	abrogates atr bona chk1 clamp claspin damaging extensively fide heterotetrameric hus1 impacting irradiation lac laco lacr lastly localizes onto orphan portion repeats repressor rhino tethering topbp1 uv
Tagcloud (Intersection) ?		checkpoint rad9