RAD9B and HUS1

Number of citations of the paper that reports this interaction (PMID 14611806)
5

Data Source:
HPRD (in vivo)

		RAD9B	HUS1
Gene Name		RAD9 homolog B (S. pombe)	HUS1 checkpoint homolog (S. pombe)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Checkpoint Clamp Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Checkpoint Clamp Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	DNA Damage Checkpoint Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Negative Regulation Of DNA Replication Response To UV Embryo Development Cellular Response To Ionizing Radiation
Pathways		G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints	G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: HUS1 HUS1B RAD1 RAD17 RAD9A	16 interactors: CD200 COPS5 DNAJC7 HDAC1 HUS1B MSH2 MSH3 MSH6 PCNA RAD1 RAD17 RAD9A RAD9B RPA1 RPA2 YWHAQ
Entrez ID		144715	3364
HPRD ID		12221	04787
Ensembl ID		ENSG00000151164	ENSG00000136273
Uniprot IDs		B4DYM6 J3KPN7 Q6WBX8	A4D2F2 O60921
PDB IDs			3A1J 3G65 3GGR
Enriched GO Terms of Interacting Partners?		DNA Damage Checkpoint Cell Cycle Checkpoint DNA Repair Cellular Response To DNA Damage Stimulus DNA Replication Cellular Response To Ionizing Radiation Cell Cycle Process DNA Metabolic Process Cell Cycle Negative Regulation Of Cell Cycle Cellular Response To Stress DNA Replication Checkpoint Cellular Response To Radiation Response To Ionizing Radiation Mitotic Cell Cycle Checkpoint Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle DNA Catabolic Process, Exonucleolytic Negative Regulation Of DNA Replication Regulation Of Mitotic Cell Cycle Response To Radiation Response To Stress Negative Regulation Of DNA Metabolic Process Mitotic Cell Cycle Process Regulation Of DNA Replication Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle DNA Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Recombination Checkpoint Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Nucleic Acid Phosphodiester Bond Hydrolysis Cellular Response To Stimulus Intra-S DNA Damage Checkpoint Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Aromatic Compound Catabolic Process Negative Regulation Of Meiotic Nuclear Division Response To Stimulus Negative Regulation Of Meiotic Cell Cycle Biosynthetic Process Substantia Nigra Development Regulation Of Meiosis Regulation Of Meiotic Cell Cycle Neural Nucleus Development Cellular Macromolecule Catabolic Process	DNA Repair Cellular Response To DNA Damage Stimulus Mismatch Repair Cell Cycle DNA Damage Checkpoint Cell Cycle Process DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To Stress Meiotic Mismatch Repair DNA Replication Positive Regulation Of Helicase Activity DNA Recombination Response To Stress Regulation Of DNA Recombination Nucleobase-containing Compound Metabolic Process Nucleotide-excision Repair, DNA Gap Filling Meiotic Cell Cycle Negative Regulation Of DNA Recombination Mitotic Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Nitrogen Compound Metabolic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Regulation Of Cell Cycle Telomere Maintenance Via Telomere Lengthening Somatic Recombination Of Immunoglobulin Gene Segments Nitrogen Compound Metabolic Process Somatic Diversification Of Immunoglobulins DNA Catabolic Process Maintenance Of DNA Repeat Elements Transcription-coupled Nucleotide-excision Repair Mitotic Cell Cycle Process Mitotic Cell Cycle Checkpoint DNA Recombinase Assembly Meiotic Nuclear Division Immunoglobulin Production Base-excision Repair Negative Regulation Of Mitotic Cell Cycle Cellular Response To Stimulus Telomere Maintenance Intra-S DNA Damage Checkpoint DNA Replication Checkpoint
Tagcloud ?		1x 3b aminobutyric anxa atg3 autophagy checkpoint enos fenofibrate gabarap homologue huvec lc3b mating metallothionein microtubule mt1x physiologically phytoalexin polyphenolic repeated resveratrol scavenger silent sirt1 umbilical vein wine	abrogates atr bona checkpoint chk1 clamp claspin damaging extensively fide heterotetrameric impacting irradiation lac laco lacr lastly localizes onto orphan portion rad1 rad9 repeats repressor rhino tethering topbp1 uv
Tagcloud (Difference) ?		1x 3b aminobutyric anxa atg3 autophagy enos fenofibrate gabarap homologue huvec lc3b mating metallothionein microtubule mt1x physiologically phytoalexin polyphenolic repeated resveratrol scavenger silent sirt1 umbilical vein wine	abrogates atr bona chk1 clamp claspin damaging extensively fide heterotetrameric impacting irradiation lac laco lacr lastly localizes onto orphan portion rad1 repeats repressor rhino tethering topbp1 uv
Tagcloud (Intersection) ?		checkpoint rad9