SYT9 and TMEM50A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYT9	TMEM50A
Description		synaptotagmin 9	transmembrane protein 50A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Clathrin-coated Endocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Synapse Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse	Cytoplasm Endoplasmic Reticulum Membrane Neuronal Cell Body Glial Cell Projection
	Molecular Function	SNARE Binding Phosphatidylserine Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Identical Protein Binding Metal Ion Binding Calcium Ion Sensor Activity	Protein Binding
	Biological Process	Chemical Synaptic Transmission Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Vesicle Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Pathways		Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Breast cancer and/or colorectal cancer ( 29698419) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551) Dietary fat liking ( 32516399) Familial lung cancer ( 29924316) Lead levels ( 26025379) Malaria ( 31844061) Phospholipid levels (plasma) ( 22359512) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)	Erythrocyte sedimentation rate ( 21700265) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		10 interacting genes: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TMBIM6 TMEM50A TRPV1 TUBB UPK1B	13 interacting genes: ABCG4 AQP6 COMT HLA-DPA1 LEPROT LEPROTL1 REEP4 SLC30A8 SYT9 TMEM14B TMEM31 TRAPPC14 XRN1
Entrez ID		143425	23585
HPRD ID		11618	05636
Ensembl ID		ENSG00000170743	ENSG00000183726
Uniprot IDs		Q86SS6	B7Z5M7 O95807 Q7RU07
PDB IDs
Enriched GO Terms of Interacting Partners?		Secretion Signal Release Synaptic Vesicle Exocytosis Neurotransmitter Secretion Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Temperature-gated Ion Channel Activity Response To Capsazepine Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Membrane Secretion By Cell Neurotransmitter Transport Regulated Exocytosis Calcium-dependent Protein Binding Vesicle-mediated Transport In Synapse Specific Granule Membrane Establishment Of Localization In Cell Calcium Channel Activity Endoribonuclease Inhibitor Activity Apical Plasma Membrane Urothelial Plaque Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Smooth Muscle Contraction Involved In Micturition GABA-ergic Synapse Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Neuromuscular Junction Positive Regulation Of Neuromuscular Synaptic Transmission Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Protein-containing Complex Assembly Synaptic Vesicle Ribbon Synapse Vesicle Monoatomic Cation Transmembrane Transport Dense Core Granule Exocytosis Metal Ion Transport Inorganic Cation Transmembrane Transport Presynaptic Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Positive Regulation Of Synaptic Transmission Vesicle Localization Learning Presynaptic Dense Core Vesicle Exocytosis Neuronal Dense Core Vesicle Exocytosis Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Structural Molecule Activity	Negative Regulation Of Growth Hormone Receptor Signaling Pathway Regulation Of Growth Hormone Receptor Signaling Pathway Nitrate Transmembrane Transporter Activity Membrane Norepinephrine Secretion Response To Peptide Catechol O-methyltransferase Activity Cholesterol Efflux Response To Cytokine Transport Vesicle Membrane Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Cellular Response To Puromycin Cellular Response To Cycloheximide PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Phosphate Starvation Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Endosome Membrane ABC-type Sterol Transporter Activity Sterol Transport Endosome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?