SYT9 and TRPV1

Number of citations of the paper that reports this interaction (PMID 15066994)
52

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SYT9	TRPV1
Gene Name		synaptotagmin IX	transient receptor potential cation channel, subfamily V, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Cell Junction Secretory Granule Membrane Synaptic Vesicle Membrane Dense Core Granule	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Postsynaptic Membrane
	Molecular Function	Transporter Activity Identical Protein Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Calmodulin Binding ATP Binding Calcium-release Channel Activity Phosphoprotein Binding
	Biological Process	Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion	Transport Cell Surface Receptor Signaling Pathway Chemosensory Behavior Ion Transmembrane Transport Thermoception Transmembrane Transport Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP
Pathways			Ion channel transport TRP channels Stimuli-sensing channels
Drugs			Alpha-Linolenic Acid Icosapent Aspartame
Diseases
GWAS		Phospholipid levels (plasma) ( 22359512)
Protein-Protein Interactions		6 interactors: CSNK1A1 NRXN1 SNAP25 SYNCRIP TRPV1 TUBB	7 interactors: CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2
Entrez ID		143425	7442
HPRD ID		11618	03648
Ensembl ID		ENSG00000170743	ENSG00000196689
Uniprot IDs		Q86SS6	E7EQ78 Q8NER1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Regulation Of Neurotransmitter Levels Neurotransmitter Transport Gephyrin Clustering Synaptic Vesicle Clustering Thermoception Neuronal Signal Transduction Regulation Of Insulin Secretion Vesicle Localization N-methyl-D-aspartate Receptor Clustering Vocal Learning CRD-mediated MRNA Stabilization Regulation Of Peptide Hormone Secretion Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Protein Complex Assembly Synapse Maturation Regulation Of Grooming Behavior Regulation Of Hormone Secretion Transport Synaptic Vesicle Docking Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Synaptic Vesicle Priming Cellular Response To ATP Receptor Localization To Synapse Regulation Of Synaptic Transmission Presynaptic Membrane Organization Auditory Behavior Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Protein Complex Assembly Neurotransmitter Uptake Cerebellar Granule Cell Differentiation Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Regulation Of Protein Secretion Chemosensory Behavior Positive Regulation Of Synapse Maturation Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Organelle Localization Cell Division Response To Auditory Stimulus Regulation Of Synapse Maturation	Positive Regulation Of Transport Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Innate Immune Response Regulation Of Nitric-oxide Synthase Activity Fc Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Regulation Of Cytokinesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Ion Transmembrane Transport Regulation Of Intracellular Transport Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Cellular Ketone Metabolic Process Alkanesulfonate Metabolic Process Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Cellular Glucuronidation Defense Response Positive Regulation Of Calcium Ion Transport Calcium-mediated Signaling Negative Regulation Of Ion Transport Positive Regulation Of Synaptic Transmission Regulation Of Phosphorus Metabolic Process Reactive Oxygen Species Metabolic Process Cellular Response To Growth Factor Stimulus Response To Calcium Ion Response To Growth Factor Regulation Of MAPK Cascade TRAM-dependent Toll-like Receptor 4 Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Tagcloud ?			6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Difference) ?			6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Intersection) ?