TMEM50A and LEPROTL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM50A	LEPROTL1
Description		transmembrane protein 50A	leptin receptor overlapping transcript like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Neuronal Cell Body Glial Cell Projection	Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Erythrocyte sedimentation rate ( 21700265) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		13 interacting genes: ABCG4 AQP6 COMT HLA-DPA1 LEPROT LEPROTL1 REEP4 SLC30A8 SYT9 TMEM14B TMEM31 TRAPPC14 XRN1	73 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35H1 SLC71A2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15
Entrez ID		23585	23484
HPRD ID		05636	09551
Ensembl ID		ENSG00000183726	ENSG00000104660
Uniprot IDs		B7Z5M7 O95807 Q7RU07	O95214 Q6FHL7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Growth Hormone Receptor Signaling Pathway Regulation Of Growth Hormone Receptor Signaling Pathway Nitrate Transmembrane Transporter Activity Membrane Norepinephrine Secretion Response To Peptide Catechol O-methyltransferase Activity Cholesterol Efflux Response To Cytokine Transport Vesicle Membrane Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Cellular Response To Puromycin Cellular Response To Cycloheximide PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Cellular Response To Phosphate Starvation Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Endosome Membrane ABC-type Sterol Transporter Activity Sterol Transport Endosome	Membrane Endoplasmic Reticulum Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Cellular Localization Myelination Axon Ensheathment SA Node Cell Action Potential Transmembrane Transport
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