CRYBA1 and CRYBB2

Number of citations of the paper that reports this interaction (PMID 17662718)
7

Data Source:
HPRD (two hybrid)

		CRYBA1	CRYBB2
Gene Name		crystallin, beta A1	crystallin, beta B2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding Protein Homodimerization Activity	Structural Molecule Activity Structural Constituent Of Eye Lens Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Lens Development In Camera-type Eye Visual Perception	Visual Perception Camera-type Eye Development Response To Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 RBPMS RHOXF2	8 interactors: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 MIP
Entrez ID		1411	1415
HPRD ID		00429	00430
Ensembl ID		ENSG00000108255	ENSG00000244752
Uniprot IDs		P05813	P43320 R4UMM2
PDB IDs			1YTQ
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Neurological System Process Regulation Of Intracellular Transport Negative Regulation Of Intracellular Transport Tubulin Complex Assembly Protein Homooligomerization Regulation Of Cellular Localization	Camera-type Eye Development Eye Development Visual Perception Sensory Perception Of Light Stimulus Sensory Organ Development Lens Development In Camera-type Eye Sensory Perception Neurological System Process Organ Development System Development Negative Regulation Of Intracellular Transport Multicellular Organismal Development Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Protein Processing Involved In Protein Targeting To Mitochondrion Tubulin Complex Assembly Negative Regulation Of Apoptotic Process Developmental Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Endothelial Cell Chemotaxis Protein Homooligomerization Negative Regulation Of Cell Death Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Transport
Tagcloud ?		17q11 assayed base betaa3 betaa3a1 bits blindness cataracts causally cczs cosegregates creates crystallin digestion intron lowers mapped morphologically mutational nlaiii opacities q12 sequenced splice splicing sutural tgagt zonular	abnormality acuity adcc adulthood arranged autosomal blindness blue bluish cataract cataracts cerulean concentric congenital cousin crystallin daughter familial lens mapped mating mildly occasional opacifications opacities presumed radially studying termination
Tagcloud (Difference) ?		17q11 assayed base betaa3 betaa3a1 bits causally cczs cosegregates creates digestion intron lowers morphologically mutational nlaiii q12 sequenced splice splicing sutural tgagt zonular	abnormality acuity adcc adulthood arranged autosomal blue bluish cataract cerulean concentric congenital cousin daughter familial lens mating mildly occasional opacifications presumed radially studying termination
Tagcloud (Intersection) ?		blindness cataracts crystallin mapped opacities