CRYBB2 and CRYBA2

Number of citations of the paper that reports this interaction (PubMedID 17662718)
29

Data Source:
HPRD (two hybrid)

		CRYBB2	CRYBA2
Description		crystallin beta B2	crystallin beta A2
Image			No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Camera-type Eye Development	Lens Development In Camera-type Eye Visual Perception
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678)	Height ( 18391951 31562340) Macular thickness ( 30535121) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure ( 28234671) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		9 interacting genes: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 LMO4 MIP	27 interacting genes: ANAPC11 ARID5A BPIFA1 C10orf55 C22orf39 CALCOCO1 CCDC33 CRYBB1 CRYBB2 CRYBB3 CTDSP1 CYSRT1 FHL3 FHL5 KRTAP11-1 KRTAP13-3 KRTAP7-1 LASP1 NFKBID OXER1 PRR22 RUSC1 TRAF2 TRIP13 UNKL VAC14 YPEL3
Entrez ID		1415	1412
HPRD ID		00430	02905
Ensembl ID		ENSG00000244752	ENSG00000163499
Uniprot IDs		P43320 R4UMM2	P53672
PDB IDs		1YTQ 7K7U
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Protein Refolding System Process Nervous System Process Tubulin Complex Assembly Response To Heat Camera-type Eye Development Contractile Muscle Fiber Unfolded Protein Binding Eye Development Response To Temperature Stimulus Apoptotic Process Involved In Morphogenesis Sensory Organ Development Apoptotic Process Involved In Development Protein Folding Negative Regulation Of Intracellular Transport Developmental Process Homotypic Cell-cell Adhesion Negative Regulation Of Protein Kinase C Signaling Identical Protein Binding Response To Hydrogen Peroxide Protein Kinase C Inhibitor Activity Ventral Spinal Cord Interneuron Differentiation Negative Regulation Of Protein-containing Complex Assembly Z Disc Regulation Of Protein Kinase C Signaling Response To Reactive Oxygen Species Gap Junction-mediated Intercellular Transport Structural Molecule Activity Lens Fiber Cell Morphogenesis Cardiac Myofibril Positive Regulation Of Anoikis Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Apoptotic Process Animal Organ Development Maintenance Of Lens Transparency Actin Filament Bundle Anterograde Axonal Protein Transport Regulation Of Programmed Cell Death Intercellular Transport Spinal Cord Association Neuron Differentiation	Structural Constituent Of Eye Lens Lens Development In Camera-type Eye
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