CRYBB2 and CRYBA4

Number of citations of the paper that reports this interaction (PubMedID 17662718)
29

Data Source:
HPRD (two hybrid)

		CRYBB2	CRYBA4
Description		crystallin beta B2	crystallin beta A4
Image
GO Annotations	Cellular Component
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Camera-type Eye Development	Lens Development In Camera-type Eye Visual Perception Camera-type Eye Development
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		Adverse response to drug ( 30420678)
Interacting Genes		9 interacting genes: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 LMO4 MIP	13 interacting genes: C1orf94 CCDC33 CEP76 CRYBB1 CRYBB2 EFEMP1 FHL5 GLI1 IKZF3 MIF4GD PRR22 STX11 TRIP6
Entrez ID		1415	1413
HPRD ID		00430	00432
Ensembl ID		ENSG00000244752	ENSG00000196431
Uniprot IDs		P43320 R4UMM2	A0A097PIJ6 P53673
PDB IDs		1YTQ 7K7U	3LWK
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Protein Refolding System Process Nervous System Process Tubulin Complex Assembly Response To Heat Camera-type Eye Development Contractile Muscle Fiber Unfolded Protein Binding Eye Development Response To Temperature Stimulus Apoptotic Process Involved In Morphogenesis Sensory Organ Development Apoptotic Process Involved In Development Protein Folding Negative Regulation Of Intracellular Transport Developmental Process Homotypic Cell-cell Adhesion Negative Regulation Of Protein Kinase C Signaling Identical Protein Binding Response To Hydrogen Peroxide Protein Kinase C Inhibitor Activity Ventral Spinal Cord Interneuron Differentiation Negative Regulation Of Protein-containing Complex Assembly Z Disc Regulation Of Protein Kinase C Signaling Response To Reactive Oxygen Species Gap Junction-mediated Intercellular Transport Structural Molecule Activity Lens Fiber Cell Morphogenesis Cardiac Myofibril Positive Regulation Of Anoikis Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Apoptotic Process Animal Organ Development Maintenance Of Lens Transparency Actin Filament Bundle Anterograde Axonal Protein Transport Regulation Of Programmed Cell Death Intercellular Transport Spinal Cord Association Neuron Differentiation
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