CRYBB2 and CRYBA4

Number of citations of the paper that reports this interaction (PMID 17662718)
7

Data Source:
HPRD (two hybrid)

		CRYBB2	CRYBA4
Gene Name		crystallin, beta B2	crystallin, beta A4
Image
Gene Ontology Annotations	Cellular Component		Cellular_component
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Identical Protein Binding Protein Homodimerization Activity	Molecular_function Structural Constituent Of Eye Lens
	Biological Process	Visual Perception Camera-type Eye Development Response To Stimulus	Visual Perception Camera-type Eye Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 MIP	3 interactors: CEP76 CRYBB1 CRYBB2
Entrez ID		1415	1413
HPRD ID		00430	00432
Ensembl ID		ENSG00000244752	ENSG00000196431
Uniprot IDs		P43320 R4UMM2	P53673
PDB IDs		1YTQ	3LWK
Enriched GO Terms of Interacting Partners?		Camera-type Eye Development Eye Development Visual Perception Sensory Perception Of Light Stimulus Sensory Organ Development Lens Development In Camera-type Eye Sensory Perception Neurological System Process Organ Development System Development Negative Regulation Of Intracellular Transport Multicellular Organismal Development Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Protein Processing Involved In Protein Targeting To Mitochondrion Tubulin Complex Assembly Negative Regulation Of Apoptotic Process Developmental Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Endothelial Cell Chemotaxis Protein Homooligomerization Negative Regulation Of Cell Death Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Transport	Visual Perception Sensory Perception Of Light Stimulus Regulation Of Centriole Replication Sensory Perception Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Neurological System Process
Tagcloud ?		abnormality acuity adcc adulthood arranged autosomal blindness blue bluish cataract cataracts cerulean concentric congenital cousin crystallin daughter familial lens mapped mating mildly occasional opacifications opacities presumed radially studying termination	22q11 absent analysis assignments backcross beta central chromosome crybb2 crybb2p1 crybb3 crystallin define e genes homologue homologues homology human interspecific located mapped mouse new region using
Tagcloud (Difference) ?		abnormality acuity adcc adulthood arranged autosomal blindness blue bluish cataract cataracts cerulean concentric congenital cousin daughter familial lens mating mildly occasional opacifications opacities presumed radially studying termination	22q11 absent analysis assignments backcross beta central chromosome crybb2p1 crybb3 define e genes homologue homologues homology human interspecific located mouse new region using
Tagcloud (Intersection) ?		crybb2 crystallin mapped