CRYBB2 and CRYGC

Number of citations of the paper that reports this interaction (PMID 11700327)
21

Data Source:
HPRD (in vitro)

		CRYBB2	CRYGC
Gene Name		crystallin, beta B2	crystallin, gamma C
Image
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Identical Protein Binding Protein Homodimerization Activity	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Visual Perception Camera-type Eye Development Response To Stimulus	Visual Perception Camera-type Eye Development
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		8 interactors: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 MIP	7 interactors: CRYAA CRYAB CRYBB2 CRYGD HSPB1 HSPB2 MIP
Entrez ID		1415	1420
HPRD ID		00430	00435
Ensembl ID		ENSG00000244752	ENSG00000163254
Uniprot IDs		P43320 R4UMM2	P07315
PDB IDs		1YTQ	1LFE
Enriched GO Terms of Interacting Partners?		Camera-type Eye Development Eye Development Visual Perception Sensory Perception Of Light Stimulus Sensory Organ Development Lens Development In Camera-type Eye Sensory Perception Neurological System Process Organ Development System Development Negative Regulation Of Intracellular Transport Multicellular Organismal Development Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Protein Processing Involved In Protein Targeting To Mitochondrion Tubulin Complex Assembly Negative Regulation Of Apoptotic Process Developmental Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Endothelial Cell Chemotaxis Protein Homooligomerization Negative Regulation Of Cell Death Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Negative Regulation Of Transport	Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Lens Development In Camera-type Eye Eye Development Sensory Organ Development Sensory Perception Neurological System Process Negative Regulation Of Intracellular Transport Response To Stimulus Response To Unfolded Protein Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Reactive Oxygen Species Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Cell Death Tubulin Complex Assembly Protein Homooligomerization Positive Regulation Of Endothelial Cell Chemotaxis Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Response To Oxidative Stress Organ Development Protein Oligomerization Regulation Of Apoptotic Process Regulation Of Intracellular Transport Apoptotic Process Involved In Development Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Bile Acid And Bile Salt Transport Cell Volume Homeostasis
Tagcloud ?		abnormality acuity adcc adulthood arranged autosomal blindness blue bluish cataract cataracts cerulean concentric congenital cousin crystallin daughter familial lens mapped mating mildly occasional opacifications opacities presumed radially studying termination	coherence cryba1 cryba2 cryba4 crybb1 crybb2 crybb3 crystallin degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retina retinal retinopathies rpe survived
Tagcloud (Difference) ?		abnormality acuity adcc adulthood arranged autosomal blindness blue bluish cataract cataracts cerulean concentric congenital cousin daughter familial lens mapped mating mildly occasional opacifications opacities presumed radially studying termination	coherence cryba1 cryba2 cryba4 crybb1 crybb3 degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retina retinal retinopathies rpe survived
Tagcloud (Intersection) ?		crybb2 crystallin