ASB6 and SH2B2

Number of citations of the paper that reports this interaction (PMID 15231829)
17

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		ASB6	SH2B2
Gene Name		ankyrin repeat and SOCS box containing 6	SH2B adaptor protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Stress Fiber Ruffle Cytoplasm Cytosol Actin Filament Plasma Membrane
	Molecular Function		Signal Transducer Activity Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Protein Binding JAK Pathway Signal Transduction Adaptor Activity Identical Protein Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	B-1 B Cell Homeostasis Signal Transduction Nervous System Development Blood Coagulation Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Cytokine-mediated Signaling Pathway Regulation Of Metabolic Process Actin Cytoskeleton Organization Intracellular Signal Transduction Regulation Of JAK-STAT Cascade Regulation Of Ras Protein Signal Transduction Antigen Receptor-mediated Signaling Pathway Brown Fat Cell Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Signaling by SCF-KIT Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP FAM9B L3MBTL3 RNF41 SH2B2 TCEB1	21 interactors: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID		140459	10603
HPRD ID		10673	16097
Ensembl ID
Uniprot IDs		Q9NWX5	O14492
PDB IDs			1Q2H
Enriched GO Terms of Interacting Partners?		Cell Maturation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Homeostasis Of Number Of Cells	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Protein Autophosphorylation Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Intracellular Signal Transduction Peptidyl-amino Acid Modification Positive Regulation Of Signal Transduction Response To Organic Substance Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Protein Phosphorylation Innate Immune Response Fc Receptor Signaling Pathway Regulation Of MAPK Cascade Regulation Of Cell Proliferation Regulation Of Immune Response Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Organonitrogen Compound Cellular Response To Peptide Signaling Neurotrophin TRK Receptor Signaling Pathway Defense Response Cell Communication Neurotrophin Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Phosphorylation Response To Growth Factor Movement Of Cell Or Subcellular Component Response To Peptide Hormone Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signaling ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Locomotion Cell Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Cell Activation Response To Peptide Response To Wounding Immune Response Regulation Of Immune System Process Cellular Response To Stimulus
Tagcloud ?			accordingly adaptor aps assembling called counteract dephosphorylation dimerization dimers hetero homo hyperphagia insects irs1 irs2 leptin obesity protecting protects psm sh2b1 sh2b1beta sh2b3 transgenes trka tyrosyl
Tagcloud (Difference) ?			accordingly adaptor aps assembling called counteract dephosphorylation dimerization dimers hetero homo hyperphagia insects irs1 irs2 leptin obesity protecting protects psm sh2b1 sh2b1beta sh2b3 transgenes trka tyrosyl
Tagcloud (Intersection) ?