CREM and EMP3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CREM	EMP3
Gene Name		cAMP responsive element modulator	epithelial membrane protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Core Promoter Sequence-specific DNA Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Glycosphingolipid Metabolic Process Signal Transduction Multicellular Organismal Development Spermatogenesis Cell Differentiation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To CAMP	Cell Death Negative Regulation Of Cell Proliferation Cell Growth Bleb Assembly
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		29 interactors: ATF1 ATXN1 CAMK2D CAMK2G CASP8AP2 CD34 CDC34 CDK1 CREB1 CREB3L1 CREBBP CSNK1A1 CSNK2A1 CSNK2A2 EMP3 FHL5 GSK3A GSK3B HDAC1 KCNIP3 MAPK3 PIAS3 PRKACA PRKCA SP100 SPI1 TAF4 TBP UBE2I	3 interactors: CREM EDA P2RX7
Entrez ID		1390	2014
HPRD ID		00444	18514
Ensembl ID		ENSG00000095794	ENSG00000142227
Uniprot IDs		Q03060	P54852
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Response To Heat Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Cardiac Muscle Hypertrophy Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transcription, DNA-templated Response To Growth Factor Cell Death Death Cellular Protein Modification Process Regulation Of Metabolic Process Cell Cycle RNA Biosynthetic Process Regulation Of Cellular Process Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Gene Expression Peptidyl-serine Phosphorylation Hypermethylation Of CpG Island Peptidyl-amino Acid Modification Nucleobase-containing Compound Metabolic Process Apoptotic Process Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Cell Surface Receptor Signaling Pathway Programmed Cell Death Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Phosphorylation Macromolecule Biosynthetic Process Cellular Response To Heat Heterocycle Metabolic Process	Response To Organophosphorus Sphingolipid Metabolic Process Response To Purine-containing Compound Phospholipid Transfer To Membrane NAD Transport Membrane Lipid Metabolic Process Positive Regulation Of Intracellular Transport Positive Regulation Of Interleukin-1 Alpha Secretion Positive Regulation Of Cytolysis Trachea Gland Development Multicellular Organismal Protein Catabolic Process Positive Regulation Of Glutamate Secretion Multicellular Organismal Protein Metabolic Process Positive Regulation Of Protein Transport Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Gamma-aminobutyric Acid Secretion Salivary Gland Cavitation Regulation Of Intracellular Transport Regulation Of Killing Of Cells Of Other Organism Bleb Assembly Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Amino Acid Transport Pore Complex Assembly Negative Regulation Of Bone Resorption Regulation Of Glutamate Secretion Phagolysosome Assembly Negative Regulation Of Bone Remodeling Positive Regulation Of Prostaglandin Secretion Regulation Of Protein Transport Negative Regulation Of Tissue Remodeling Hair Follicle Placode Formation Regulation Of Mitochondrial Depolarization Membrane Protein Ectodomain Proteolysis Positive Regulation Of Interleukin-1 Beta Secretion Regulation Of Establishment Of Protein Localization Positive Regulation Of Icosanoid Secretion Positive Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Interleukin-1 Secretion Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Transport Regulation Of Interleukin-1 Beta Secretion Ectoderm Development Cytolysis Positive Regulation Of Fatty Acid Transport Regulation Of Protein Localization Response To ATP Positive Regulation Of Intracellular Signal Transduction Response To Organonitrogen Compound Positive Regulation Of Interleukin-1 Beta Production Trachea Development
Tagcloud ?		27mer abp activin artefact artefactual basally bluescript bouin crna cystatin digoxigenin distinguishable inhibin ix leptotene promotor propria protamine pyronin rbs riboprobes seminiferous sgp spermatocytes sulphated t7 trichloroacetic tubules viii	19q13 adhesion bioinformatics cavities crosstalk designing erbb2 estimates guided immunoblot indicator innovative integrins kaplan log meier neoplastic oncogene pyelocalyceal rank selecting stratification tract transcriptase upper ureter urinary urothelial validate
Tagcloud (Difference) ?		27mer abp activin artefact artefactual basally bluescript bouin crna cystatin digoxigenin distinguishable inhibin ix leptotene promotor propria protamine pyronin rbs riboprobes seminiferous sgp spermatocytes sulphated t7 trichloroacetic tubules viii	19q13 adhesion bioinformatics cavities crosstalk designing erbb2 estimates guided immunoblot indicator innovative integrins kaplan log meier neoplastic oncogene pyelocalyceal rank selecting stratification tract transcriptase upper ureter urinary urothelial validate
Tagcloud (Intersection) ?